       Document 1001
 DOCN  M9651001
 TI    Cyclospora cayetanensis infection in patients with and without AIDS:
       biliary disease as another clinical manifestation.
 DT    9505
 AU    Sifuentes-Osornio J; Porras-Cortes G; Bendall RP; Morales-Villarreal F;
       Reyes-Teran G; Ruiz-Palacios GM; Department of Infectious Diseases,
       Instituto Nacional de la; Nutricion Salvador Zubiran, Mexico City,
       Mexico.
 SO    Clin Infect Dis. 1995 Nov;21(5):1092-7. Unique Identifier : AIDSLINE
       MED/96125987
 AB    We describe patients with and without AIDS who had Cyclospora
       cayetanensis infection; these patients were seen at a tertiary care
       teaching hospital in Mexico City because of diarrheal disease. C.
       cayetanensis was detected by examination of fresh fecal preparations and
       acid-fast staining of fecal smears; the presence of other bacteria and
       parasites was excluded by standard methods. Fecal specimens from 12
       patients contained C. cayetanensis. The overall mean duration of illness
       was 94 days. Seven of the 12 patients had AIDS; these patients presented
       with more weight loss than did patients without AIDS (P = .04). The
       patients with AIDS also tended to have a more prolonged illness. Two
       patients with AIDS had biliary disease that resolved when they received
       therapy with trimethoprim-sulfamethoxazole for cyclospora infection; the
       excretion of oocysts also ceased. Our data confirm that C. cayetanensis
       causes diarrhea in humans and a significant weight loss in patients with
       AIDS. In addition, Cyclospora could be involved in biliary disease in
       patients with AIDS.
 DE    Adult  Aged  Animal  AIDS-Related Opportunistic
       Infections/*COMPLICATIONS/*DIAGNOSIS/  PARASITOLOGY  Biliary Tract
       Diseases/*COMPLICATIONS/PARASITOLOGY/  ULTRASONOGRAPHY
       Coccidia/ISOLATION & PURIF/PATHOGENICITY
       Coccidiosis/*COMPLICATIONS/*DIAGNOSIS/PARASITOLOGY
       Diarrhea/COMPLICATIONS/PARASITOLOGY  Feces/PARASITOLOGY  Female  Human
       Male  Mexico  Middle Age  Trimethoprim-Sulfamethoxazole
       Combination/THERAPEUTIC USE  Weight Loss  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

