       Document 0989
 DOCN  M9650989
 TI    Simultaneous occurrence of acute myocarditis and reactivated Chagas'
       disease in a patient with AIDS.
 DT    9505
 AU    Sartori AM; Lopes MH; Caramelli B; Duarte MIK; Pinto PL; Neto V; Amato
       Shikanai-Yasuda M; Department of Infectious and Parasitic Diseases,
       Faculdade de; Medicina, Universidade de Sao Paulo, Brazil.
 SO    Clin Infect Dis. 1995 Nov;21(5):1297-9. Unique Identifier : AIDSLINE
       MED/96126021
 AB    Myocarditis is not an uncommon finding in autopsy series of patients
       with AIDS, although clinically important myocarditis is rarely noted. We
       describe a 50-year-old woman with AIDS and chronic chagasic
       megaesophagus, without previous cardiac abnormalities, who experienced
       reactivation of Chagas' disease, characterized by the finding of
       Trypanosoma cruzi via direct microscopic examination of the buffy coat,
       xenodiagnosis, and blood culture; she developed fatal acute myocarditis.
       Reactivation of Chagas' disease in patients with AIDS has been reported,
       but in the great majority of cases it has been associated with central
       nervous system involvement. In areas where Chagas' disease is endemic,
       reactivation may occur in patients with AIDS.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Acute Disease  Animal
       AIDS-Related Opportunistic Infections/COMPLICATIONS  Case Report  Chagas
       Disease/*COMPLICATIONS/PARASITOLOGY  Fatal Outcome  Female  Human
       Middle Age  Myocarditis/*COMPLICATIONS/PARASITOLOGY  Recurrence
       Toxoplasmosis, Cerebral/COMPLICATIONS  Trypanosoma cruzi/ISOLATION &
       PURIF  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

