       Document 0967
 DOCN  M9650967
 TI    Intestinal histoplasmosis in AIDS patients: report of three cases
       observed in France and review of the literature.
 DT    9505
 AU    Trylesinski A; Carbonnel F; Bouchaud O; Beaugerie L; Gharakanian S;
       Rozenbaum W; Cosnes J; Gendre JP; Le Quintrec Y; Service de
       Gastroenterologie et de Nutrition, Hopital; Rothschild, Paris, France.
 SO    Eur J Gastroenterol Hepatol. 1995 Jul;7(7):679-83. Unique Identifier :
       AIDSLINE MED/96022534
 AB    We report three cases of colonic histoplasmosis observed in a
       non-endemic area in patients with AIDS. The patients presented with
       fever, abdominal pain and an abdominal mass in the right lower quadrant.
       Diagnosis was obtained using Gomori-Crocott staining of endoscopic or
       surgical biopsies. One patient died without specific treatment and two
       patients had a complete remission when treated with intravenous
       amphotericin B but suffered a relapse when given oral itraconazole.
       Thus, physicians in areas where intestinal histoplasmosis is not endemic
       should be aware of the condition. Diagnosis can easily be obtained using
       Gomori-Crocott staining of colonoscopic biopsies; this should avoid
       unnecessary laparotomies and allow specific treatment to be instituted
       rapidly.
 DE    Adult  Amphotericin B/THERAPEUTIC USE  Antibiotics,
       Antifungal/THERAPEUTIC USE  AIDS-Related Opportunistic
       Infections/DIAGNOSIS/DRUG THERAPY/  *EPIDEMIOLOGY/MICROBIOLOGY  Case
       Report  Colonic Diseases/DIAGNOSIS/DRUG THERAPY/EPIDEMIOLOGY/
       *MICROBIOLOGY  Female  France/EPIDEMIOLOGY
       Histoplasmosis/DIAGNOSIS/DRUG THERAPY/*EPIDEMIOLOGY  Human  Male
       JOURNAL ARTICLE  REVIEW  REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

