       Document 0943
 DOCN  M9650943
 TI    The effect of zinc supplementation in experimentally induced Toxoplasma
       gondii infection.
 DT    9505
 AU    Tasci S; Sengil AZ; Altindis M; Arisoy K; Department of Microbiology,
       Medical Faculty of Celal Bayar; University, Manisa, Turkey.
 SO    J Egypt Soc Parasitol. 1995 Dec;25(3):745-51. Unique Identifier :
       AIDSLINE MED/96116659
 AB    The effect of zinc added diet on cellular immunity in toxoplasmosis was
       investigated on 50 male wistar albino rats. Total lymphocyte CB8 count
       were found higher in the infected group when compared to the control
       group (P < 0.001). The relative increase of CD8 was found to be
       responsible for the decrease in ratio. In the infected group, there was
       a slight decrease in CD4 count but it was statistically insignificant.
       While no significant differences in serum zinc level were observed
       between the groups, there was a positive correlation with CD8 count in
       infected group (r = 0.005, P < 0.05). As a result, zinc added diet in
       toxoplasmosis stimulated the cellular immunity, increased CD8 and total
       lymphocytes.
 DE    Animal  CD4-CD8 Ratio  CD4-Positive T-Lymphocytes/*DRUG
       EFFECTS/IMMUNOLOGY  CD8-Positive T-Lymphocytes/*DRUG EFFECTS/IMMUNOLOGY
       Food, Fortified  Immunity, Cellular/DRUG EFFECTS  Male  Rats  Rats,
       Wistar  Toxoplasmosis, Animal/BLOOD/*IMMUNOLOGY  Zinc/ADMINISTRATION &
       DOSAGE/BLOOD/*PHARMACOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

