       Document 0447
 DOCN  M9640447
 TI    Mycobacterial infection in Mexican AIDS patients.
 DT    9604
 AU    Molina-Gamboa JD; Ponce-de-Leon S; Sifuentes-Osornio J; Bobadilla del
       Valle M; Ruiz-Palacios GM; Department of Infectious Diseases, National
       Institute of; Nutrition, Mexico City, Mexico.
 SO    J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Jan 1;11(1):53-8.
       Unique Identifier : AIDSLINE MED/96130047
 AB    To describe the characteristics of mycobacterial infection in Mexico, we
       reviewed records from patients who were seen at the AIDS Clinic of the
       National Institute of Nutrition in Mexico City from 1983 to 1992. Of 460
       AIDS patients, 118 (25.6%) were found to have mycobacterial infections
       by positive Ziehl-Neelsen stain, culture, or both. Cultures were
       completed for 66 of the 118 stain-positive specimens. Mycobacterium
       tuberculosis was the most common species found (n = 13), followed by M.
       avium complex (n = 12); 21 infections were identified a nonspecific
       mycobacteria other than tuberculosis (MOTT) and 20 infections were from
       species other than tuberculosis. Susceptibility testing was performed in
       only two tuberculosis cases, with one strain showing multidrug
       resistance. We conclude that mycobacterial infection is common among our
       AIDS population, and MOTT may be at least as common as M. tuberculosis.
       Previous reports of the rarity of MOTT could be related to the lack of
       adequate diagnostic methods in developing countries.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adolescence  Adult
       Aged  Antitubercular Agents/THERAPEUTIC USE  AIDS-Related Opportunistic
       Infections/DRUG THERAPY/*EPIDEMIOLOGY/  ETIOLOGY  Drug Therapy,
       Combination  Female  Human  Male  Mexico/EPIDEMIOLOGY  Microbial
       Sensitivity Tests  Middle Age  Mycobacterium avium Complex/ISOLATION &
       PURIF  Mycobacterium avium-intracellulare Infection/DRUG THERAPY/
       EPIDEMIOLOGY/ETIOLOGY  Mycobacterium tuberculosis/ISOLATION & PURIF
       Mycobacterium Infections/DRUG THERAPY/*EPIDEMIOLOGY/ETIOLOGY  Survival
       Rate  Tuberculosis/DRUG THERAPY/EPIDEMIOLOGY/ETIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

