       Document 0427
 DOCN  M9640427
 TI    Validity of intravenous drug abusers' self-reported changes in HIV
       high-risk drug use behaviors.
 DT    9604
 AU    Greenfield L; Bigelow GE; Brooner RK; Behavioral Pharmacology Research
       Unit, Johns Hopkins University; School of Medicine, Baltimore, MD 21224,
       USA.
 SO    Drug Alcohol Depend. 1995 Aug;39(2):91-8. Unique Identifier : AIDSLINE
       MED/96098401
 AB    The HIV-1 high-risk drug use behavior of intravenous drug abusers was
       assessed both retrospectively (for 6 months) and prospectively (for 6
       months) via structured interview and urinalysis testing. Subjects were
       281 intravenous drug abusers, 146 enrolled in outpatient methadone
       treatment (Treatment group) and 135 not in treatment (Community group).
       The Treatment group reported fewer drug injections and less needle
       sharing and had fewer positive urinalyses for opiates and cocaine than
       did the Community group. Reported drug injection and needle sharing
       declined over time, and an increasing proportion of subjects reported
       abstinence from these behaviors. In contrast to the behavioral reports
       of subjects, positive urinalyses indicating opiate and/or cocaine use
       did not decline over time. Almost half (45.8%) of the reported increase
       in injection abstinence from intake to month six was disconfirmed by
       urinalysis. In contrast to this large discrepancy regarding reported
       behavior change, there was good agreement between reported injection
       abstinence and urinalysis results at single points in time. These data
       indicate that the validity of the reported HIV-1 risk behavior change of
       drug abusers may be less than that of reported risk behavior occurrence.
       The data raise important questions about the validity of reported
       reductions in high-risk drug use behaviors, and indicate the importance
       of using biological indicators of HIV-1 risk behavior (such as
       urinalysis) whenever possible.
 DE    Adult  Cocaine  Female  Heroin Dependence/PSYCHOLOGY/REHABILITATION
       Human  HIV Infections/*PREVENTION & CONTROL/PSYCHOLOGY/TRANSMISSION
       *HIV-1  *Knowledge, Attitudes, Practice  Male  Methadone/THERAPEUTIC USE
       Middle Age  Needle Sharing/PSYCHOLOGY  Personality
       Assessment/*STATISTICS & NUMER DATA  Prospective Studies
       Reproducibility of Results  Retrospective Studies  Substance Abuse
       Detection  Substance Abuse, Intravenous/PSYCHOLOGY/*REHABILITATION
       Substance Dependence/PSYCHOLOGY/REHABILITATION  Support, U.S. Gov't,
       P.H.S.  Truth Disclosure  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

