       Document 0421
 DOCN  M9640421
 TI    Low birth weight and genital infections. An incident case-referent
       study.
 DT    9604
 AU    Bique Osman N; Folgosa E; Gonzalez C; Bergstrom S; Department of
       Obstetrics and Gynaecology, Central Hospital,; Maputo, Mozambique.
 SO    Gynecol Obstet Invest. 1995;40(3):183-9. Unique Identifier : AIDSLINE
       MED/96121445
 AB    In an attempt to elucidate the potential association between genital
       infections and low birth weight (LBW) births, 51 women with LBW neonates
       were identified and compared to 51 women with normal birthweight (NBW)
       neonates. Both groups were matched according to age and parity. All
       women were subjected to interviews regarding socioeconomic background
       and obstetric history. The were examined clinical and tested regarding
       serum haemoglobin, malaria parasitaemia, syphilis and HIV serology.
       Cultures were taken from the vagina, endocervix, amniotic fluid and from
       various sites of newborn, including the conjunctivae and the stomach and
       from the interior of the placenta. Whilst socioeconomic background
       factors did not differ among cases and referents, previous neonatal
       death did. Significant differences were also found in mid-upper-arm
       circumference (OR 3.08) and body mass index (OR 6.00). The prevalence of
       alleged risk factors according to the antenatal card was similar among
       cases and referents. Birthweight < 2,000 g was significantly more often
       associated with chorioamnionitis than birthweight between 2,000 and
       2,499 g (OR 5.46). Bacteriological findings did not show significant
       differences in cases and referents. Haemoglobin values and prevalence of
       malaria parasitaemia were similar as was the neonatal mortality. It is
       concluded that LBW births is difficult to predict by use of alleged risk
       factors in existing antenatal cards.
 DE    Adolescence  Adult  Age Factors  Amniotic Fluid/MICROBIOLOGY  Cervix
       Uteri/MICROBIOLOGY  Chorioamnionitis/COMPLICATIONS/MICROBIOLOGY  Female
       Genital Diseases, Female/*COMPLICATIONS/MICROBIOLOGY  Human  HIV
       Seropositivity  Infant Mortality  *Infant, Low Birth Weight  Infant,
       Newborn  Infection/*COMPLICATIONS  Malaria/COMPLICATIONS  Parity
       Pregnancy  Support, Non-U.S. Gov't  Syphilis/COMPLICATIONS
       Vagina/MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

