       Document 0396
 DOCN  M9640396
 TI    Genital infections in the aetiology of late fetal death: an incident
       case-referent study.
 DT    9604
 AU    Osman NB; Folgosa E; Gonzales C; Bergstrom S; Department of Obstetrics
       and Gynecology, Central Hospital,; Maputo, Mozambique.
 SO    J Trop Pediatr. 1995 Oct;41(5):258-66. Unique Identifier : AIDSLINE
       MED/96102585
 AB    Women with prelabour fetal death in the third trimester were recruited
       in order to study the association between intra-uterine death and
       maternal genital colonization of bacteria. Fifty-eight women with
       verified fetal death were compared with a group of 58 women matched for
       age, parity and gestational length (the first referent group) and with
       women delivering liveborn neonates (second referent group). Cultures
       from the vagina, the endocervix, the amniotic fluid, the placenta, the
       conjunctivae of the newborn and the secretion of gastric aspirate of the
       newborn were carried out. Blood was taken for haemoglobin, thick film
       (malaria) and syphilis and HIV serology. Cases were more affected by
       previous stillbirths than first referents (OR = 11.88). Preterm delivery
       was significantly more common in cases than in second referents (OR =
       57.70). Cases had significantly more often < 3 ANC visits (OR = 2.81).
       Cases had a lower body mass index than first referents (OR = 2.38).
       Temperature > or = 37 degrees C was 12 times more frequent in cases than
       in first referents (OR = 21.20) and four times more frequent than in
       second referents (OR = 6.60). Average birth weight among stillborns was
       1954 g and in liveborns 3223 g (P = 0.001). The corresponding prevalence
       of LBW was 78% in cases and 0% among second referents (P < 0.001).
       Histological chorioamnionitis was significantly prevalent in cases than
       in second referents (OR = 4.97). Syphilis was significantly more common
       in cases than in first (OR = 7.71) and in second referents (OR =
       5.30).(ABSTRACT TRUNCATED AT 250 WORDS)
 DE    Adolescence  Adult  Bacterial Infections/*COMPLICATIONS  Case-Control
       Studies  Female  Fetal Death/EPIDEMIOLOGY/*MICROBIOLOGY  Genital
       Diseases, Female/*MICROBIOLOGY  Human  Mozambique/EPIDEMIOLOGY  Odds
       Ratio  Pregnancy  Pregnancy Complications, Infectious/*MICROBIOLOGY
       Pregnancy Trimester, Third  Risk Factors  Support, Non-U.S. Gov't
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

