       Document 0329
 DOCN  M9640329
 TI    Detection of immunodeficiencies and persistent infections by urinary
       neopterin measurement.
 DT    9604
 AU    Hara T; Matsuo M; Tasaki R; Miyazaki S; Bamba M; Division of Child
       Neurology, Tottori University School of; Medicine, Japan.
 SO    Acta Paediatr Jpn. 1995 Oct;37(5):575-8. Unique Identifier : AIDSLINE
       MED/96094004
 AB    We evaluated the clinical significance of measurement of urinary
       neopterin levels in primary immunodeficiencies and persistent infections
       exclusively at afebrile or asymptomatic periods. Despite the
       examinations at afebrile or asymptomatic periods, urinary neopterin
       levels were elevated in some patients with primary immunodeficiencies
       and in patients with persistent infections of human immunodeficiency
       virus (HIV) or Epstein-Barr virus (EBV). Therefore, urinary neopterin
       measurement at afebrile periods will be useful as one of the screening
       tests in the detection of such disorders among children with occasional
       episodes of infections.
 DE    Adolescence  Adult  Biological Markers/URINE  Biopterin/*ANALOGS &
       DERIVATIVES/URINE  Child  Child, Preschool  Female  Human  Immunologic
       Deficiency Syndromes/*DIAGNOSIS  Infection/*DIAGNOSIS  Male  Predictive
       Value of Tests  Support, Non-U.S. Gov't  CLINICAL TRIAL  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

