       Document 0328
 DOCN  M9640328
 TI    Long-term sequential changes of antibody to p40tax in HTLV-I carrier
       mothers and children.
 DT    9604
 AU    Kusuhara K; Ueda K; Tokugawa K; Miyazaki C; Okada K; Sawada T;
       Department of Pediatrics, Faculty of Medicine, Kyushu University,;
       Fukuoka, Japan.
 SO    Acta Paediatr Jpn. 1995 Oct;37(5):651-3. Unique Identifier : AIDSLINE
       MED/96094022
 AB    Antibody to p40tax (anti-p40tax) in serum specimens obtained
       sequentially from a human T cell lymphotropic virus type I carrier
       population of mothers and children were assayed. The prevalences of
       anti-p40tax at the initial sampling were 88% (7/8) in children and 55%
       (16/29) in mothers. Two of the seven positive children lost their
       anti-p40tax during the investigation period, resulting in a final
       prevalence of 63% (5/8) in children. However, anti-p40tax status was
       constant in all the 22 mothers with multiple serum samples (15 remained
       positive and seven remained negative). A decline in the absorbance value
       of EIA for anti-p40tax was observed in seven of the 15 anti-p40tax
       positive mothers. This decline may result in the disappearance of
       anti-p40tax in some of them.
 DE    Adolescence  Adult  Antibodies, Viral/*METABOLISM  Carrier
       State/*IMMUNOLOGY  Child  Child, Preschool  Disease Transmission,
       Vertical  Family Health  Female  Gene Products, tax/*IMMUNOLOGY  Human
       HTLV-I Infections/*IMMUNOLOGY/TRANSMISSION  Middle Age  *Mothers
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

