       Document 0239
 DOCN  M9640239
 TI    Acute hepatic and renal failure caused by Pneumocystis carinii in
       patients with AIDS.
 DT    9604
 AU    Boldorini R; Guzzetti S; Meroni L; Quirino T; Cristina S; Monga G;
       Dipartimento di Scienze Mediche, II Facolta di Medicina e; Chirurgia di
       Novara-Universita di Torino, Italy.
 SO    J Clin Pathol. 1995 Oct;48(10):975-8. Unique Identifier : AIDSLINE
       MED/96138173
 AB    Clinical and pathological findings are described in two AIDS patients
       with Pneumocystis carinii infection who received prophylactic treatment
       with nebulised pentamidine and developed unusual hepatic and renal
       failure. Histological examination showed clumps of P carinii massively
       obstructing hepatic sinuses and portal vessels in the first patient, and
       merular and intertubular capillaries in the second. These findings could
       explain the unusual clinical features, characterised by acute hepatic
       and renal failure.
 DE    Adult  Antifungal Agents/THERAPEUTIC USE  AIDS-Related Opportunistic
       Infections/*COMPLICATIONS  Case Report  Fatal Outcome  Female  Human
       Kidney Failure/*MICROBIOLOGY/PATHOLOGY  Liver
       Failure/*MICROBIOLOGY/PATHOLOGY  Male  Pentamidine/THERAPEUTIC USE
       Pneumocystis carinii Infections/*COMPLICATIONS  Pneumonia, Pneumocystis
       carinii/DRUG THERAPY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

