       Document 0229
 DOCN  M9640229
 TI    Mycobacterium avium complex sputum isolates from patients with
       respiratory symptoms in Guinea-Bissau.
 DT    9604
 AU    Koivula T; Hoffner S; Winqvist N; Naucler A; Dias F; Lacerda L; Svenson
       S; Norberg R; Kallenius G; Swedish Institute for Infectious Disease
       Control, Karolinska; Institute, Stockholm, Sweden.
 SO    J Infect Dis. 1996 Jan;173(1):263-5. Unique Identifier : AIDSLINE
       MED/96132495
 AB    In total, 814 patients with clinically suspected tuberculosis were
       examined at the Raoul Follerau Hospital in Bissau, Guinea-Bissau. Sputum
       samples were collected, and cultures were grown on Lowenstein-Jensen
       medium. Isolates were further characterized by standard biochemical
       methods and nucleic acid probes for Mycobacterium tuberculosis and
       Mycobacterium avium complex (MAC). Serum samples were collected and
       analyzed for antibodies against human immunodeficiency virus (HIV) types
       1 and 2. Of 17 patients who had MAC organisms in sputum, 2 were
       HIV-2-positive and none was HIV-1-positive. Of the total 814 patients,
       189 had culture-verified tuberculosis; 36 (19%) of them were
       HIV-2-positive. Thus, of 206 patients with sputum culture positive for
       M. tuberculosis or MAC, 17 (8%) had MAC organisms in sputum. MAC
       infection may be the cause of some treatment failures in areas where MAC
       pulmonary infection is common.
 DE    Adult  Bacteriological Techniques  Enzyme-Linked Immunosorbent Assay
       Female  Guinea-Bissau/EPIDEMIOLOGY  Human  HIV Antibodies/ANALYSIS  HIV
       Infections/COMPLICATIONS/EPIDEMIOLOGY/*MICROBIOLOGY  HIV Seropositivity
       *HIV-1  *HIV-2  Male  Mycobacterium avium Complex/*ISOLATION & PURIF
       Mycobacterium avium-intracellulare Infection/COMPLICATIONS/
       EPIDEMIOLOGY/*MICROBIOLOGY  Mycobacterium tuberculosis/ISOLATION & PURIF
       Sputum/*MICROBIOLOGY  Support, Non-U.S. Gov't  Tuberculosis,
       Pulmonary/COMPLICATIONS/EPIDEMIOLOGY/*MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

