       Document 0132
 DOCN  M9640132
 TI    Human papillomavirus-associated malignancies in HIV-positive men and
       women.
 DT    9604
 AU    Palefsky J; Medical Center, University of California at San Francisco
       94143,; USA.
 SO    Curr Opin Oncol. 1995 Sep;7(5):437-41. Unique Identifier : AIDSLINE
       MED/96076279
 AB    Human papillomavirus (HPV) infections of the anogenital tract and
       HPV-associated anogenital neoplasia are commonly found in HIV-positive
       men and women. Although there is little evidence suggesting that the
       incidence of invasive cervical cancer is increased in HIV-positive
       women, the incidence of invasive anal cancer may be increased in
       HIV-positive men. Among HIV-positive women, cervical intraepithelial
       neoplasia progresses more rapidly and recurs more often after primary
       therapy than in HIV-negative women. HPV infection and HPV-associated
       disease are often multifocal in HIV-positive women, and they may be
       found in both the vulva and the anus. Cervical cytology appears to be
       adequate as a screening tool for cervical intraepithelial neoplasia in
       HIV-positive women, but the high recurrence rate and multifocal nature
       of this disease reinforces the need for careful evaluation and follow-up
       of the entire anogenital tract in these women.
 DE    Anus Diseases/VIROLOGY  Anus
       Neoplasms/COMPLICATIONS/EPIDEMIOLOGY/VIROLOGY  Cervical Intraepithelial
       Neoplasia/VIROLOGY  Cervix Diseases/VIROLOGY  Cervix
       Neoplasms/COMPLICATIONS/EPIDEMIOLOGY/VIROLOGY  Female  Human  HIV
       Infections/*COMPLICATIONS  Male  Neoplasms/*COMPLICATIONS
       *Papillomavirus, Human  Papovaviridae Infections/*COMPLICATIONS  Tumor
       Virus Infections/*COMPLICATIONS  JOURNAL ARTICLE  REVIEW  REVIEW,
       TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

