       Document 0130
 DOCN  M9640130
 TI    An integrated approach to the epidemiology of Kaposi's sarcoma.
 DT    9604
 AU    Jacobson LP; Armenian HK; School of Hygiene and Public Health, Johns
       Hopkins University,; Baltimore, MD 21205, USA.
 SO    Curr Opin Oncol. 1995 Sep;7(5):450-5. Unique Identifier : AIDSLINE
       MED/96076281
 AB    As an AIDS-defining illness, Kaposi's sarcoma primarily occurs among
       HIV-infected homosexual men in developed countries and among men and
       women in Africa. Except in Africa, Kaposi's sarcoma was rarely diagnosed
       prior to the AIDS epidemic. The clustering of cases geographically and
       by gender suggest an environmental influence. Epidemiologic evidence of
       an infectious cofactor for the disease is presented with the recent
       findings of herpetic-like viral DNA in Kaposi's sarcoma tissue.
       Observations indicate that this putative cofactor is sexually
       transmitted. A model is provided that integrates the virologic and
       epidemiologic components in the etiology of Kaposi's sarcoma.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/EPIDEMIOLOGY  Cohort
       Studies  Female  Human  HIV Infections/*COMPLICATIONS/EPIDEMIOLOGY  Male
       Risk Factors  Sarcoma, Kaposi's/*EPIDEMIOLOGY/ETIOLOGY/*VIROLOGY
       Space-Time Clustering  Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

