       Document 0110
 DOCN  M9640110
 TI    [The clinical characteristics of pleural tuberculosis in patients with
       and without human immunodeficiency virus infection]
 DT    9604
 AU    Cordero PJ; Gil Suay V; Greses JV; Soler JJ; Perpina M; Sanchis F;
       Sanchis J; Servicio de Neumologia, Hospital Universitario La Fe,
       Valencia.
 SO    Arch Bronconeumol. 1995 Dec;31(10):512-8. Unique Identifier : AIDSLINE
       MED/96136389
 AB    OBJECTIVE: To determine whether or not there are differences in the
       characteristics of pleural tuberculosis (PT) related to whether patients
       are or are not infected by human immunodeficiency virus (HIV). METHODS:
       We conducted a retrospective study of the medical histories of patients
       diagnosed of PT in our hospital between 1986 and 1993. RESULTS: We found
       no significant differences in the proportions of tuberculosis patients
       with or without HIV infection (8% versus 11%) who were diagnosed of PT.
       Of the 119 patients diagnosed of PT, 10% were also HIV positive. The HIV
       patients had more serious forms of PT, and among them there was a higher
       incidence of pleural discharge, more isolations of Mycobacterium
       tuberculosis in sputum and pleural fluid (42% and 45% versus 13% and
       15%, p < 0.05), and more deaths before end of treatment (17% versus 1%,
       p < 0.05). The HIV patients had a lower rate of positive results in
       Mantoux's intradermal reaction test (17% versus 67%, p < 0.01), however,
       and fewer positive results for pleural biopsy (36% versus 84% positivity
       for granulomas, p < 0.01). CONCLUSIONS: The frequency of PT was similar
       for subjects with and without HIV infection in our study. In patients
       with both HIV and PT pleural fluid and sputum cultures are more useful
       diagnostic tools than pleural biopsy, and the former tests should
       therefore be stressed.
 DE    Adolescence  Adult  AIDS-Related Opportunistic
       Infections/*DIAGNOSIS/MICROBIOLOGY  Biopsy, Needle  Comparative Study
       English Abstract  Female  Human  *HIV-1  Male  Mycobacterium
       tuberculosis/ISOLATION & PURIF  Odds Ratio  Pleura/PATHOLOGY  Pleural
       Effusion/DIAGNOSIS/MICROBIOLOGY  Retrospective Studies  Statistics,
       Nonparametric  Tuberculin Test  Tuberculosis,
       Pleural/*DIAGNOSIS/MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

