       Document 0071
 DOCN  M9640071
 TI    A follow-up study on spastic paraparesis in Japanese HAM/TSP.
 DT    9604
 AU    Kuroda Y; Yukitake M; Kurohara K; Takashima H; Matsui M; Department of
       Internal Medicine, Saga Medical School, Japan.
 SO    J Neurol Sci. 1995 Oct;132(2):174-6. Unique Identifier : AIDSLINE
       MED/96098607
 AB    We followed 24 patients with HTLV-I-associated myelopathy (HAM) for 4-12
       years (mean 7 years) and assessed longitudinal changes of their spastic
       paraparesis by Kurtzke's Disability Status Scale (DSS). The DSS score of
       spastic paraparesis was unchanged in 18 patients (75%), advanced
       (worsened) by two in 1 patient and by one in 3 patients, and declined
       (improved) by one in 2 patients during the follow-up period. The results
       demonstrated that HAM presents with a variety of clinical courses
       including spontaneous improvement.
 DE    Adult  Aged  Anti-Inflammatory Agents, Steroidal/THERAPEUTIC USE
       Cerebellar Ataxia/PHYSIOPATHOLOGY  Disability Evaluation  Disease
       Progression  Female  Follow-Up Studies  Gamma-Globulins/THERAPEUTIC USE
       Human  Japan  Male  Middle Age  Paraparesis, Tropical
       Spastic/COMPLICATIONS/*PHYSIOPATHOLOGY/  THERAPY
       Prednisolone/THERAPEUTIC USE  CLINICAL TRIAL  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

