       Document 0632
 DOCN  M9630632
 TI    [Neuropsychological development of children born to HIV-positive
       mothers]
 DT    9603
 AU    Piazza F; Astori MG; Maccabruni A; Caselli D; Bossi G; Lanzi G; Istituto
       Neurologico C. Mondino di Pavia, Italia.
 SO    Pediatr Med Chir. 1995 Jul-Aug;17(4):331-3. Unique Identifier : AIDSLINE
       MED/96093231
 AB    138 children born to HIV infected mothers (58 HIV infected and 80
       seroreverted uninfected) were followed up at the Institute of Infectious
       Diseases of the University of Pavia. All patients had an evaluation of
       neurological assessment every three months done by a pediatric
       neurologist (Amiel-Tison and Towen) and an evaluation of psychological
       assessment by observation of child-mother interaction. The development
       quotient was examined using the Griffiths Scales and mental development
       using the Wisc-R scale. The incidence of Central Nervous System
       involvement was 36% in children with symptomatic HIV infection, the hump
       of incidence of severe encephalopathy was in the first 4 or 5 year of
       life, another hump (smaller) was in preadolescence. Development deficit
       and psychological problems were discovered both in asymptomatic infected
       and in non infected children, without difference of percentage between
       the two groups.
 DE    Acquired Immunodeficiency Syndrome/PSYCHOLOGY/TRANSMISSION  Age Factors
       Central Nervous System Diseases/*DIAGNOSIS  Child  *Child Development
       Child, Preschool  Comparative Study  English Abstract  Female  Human
       HIV Infections/PSYCHOLOGY/*TRANSMISSION  *HIV Seropositivity  Infant
       Infant, Newborn  Male  Pregnancy  *Pregnancy Complications, Infectious
       Psychological Tests  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

