       Document 0601
 DOCN  M9630601
 TI    Lycorine alkaloids from Hymenocallis littoralis.
 DT    9603
 AU    Lin LZ; Hu SF; Chai HB; Pengsuparp T; Pezzuto JM; Cordell GA;
       Ruangrungsi N; Department of Medicinal Chemistry and Pharmacognosy,
       College of; Pharmacy, University of Illinois at Chicago 60612, USA.
 SO    Phytochemistry. 1995 Nov;40(4):1295-8. Unique Identifier : AIDSLINE
       MED/96038661
 AB    From Hymenocallis littoralis, one new alkaloid, named littoraline,
       together with 13 known lycorine alkaloids and one lignan, were isolated.
       The structure and NMR assignments of this new alkaloid were determined
       by 1D and 2D NMR techniques. Littoraline showed inhibitory activity of
       HIV reverse transcriptase, and lycorine and haemanthamine showed potent
       in vitro cytotoxicity.
 DE    Alkaloids/CHEMISTRY/*ISOLATION & PURIF/PHARMACOLOGY  Antineoplastic
       Agents, Phytogenic/CHEMISTRY/*ISOLATION & PURIF/  PHARMACOLOGY  Human
       HIV-1/ENZYMOLOGY  Nuclear Magnetic Resonance  Reverse Transcriptase
       Inhibitors/CHEMISTRY/*ISOLATION & PURIF/  PHARMACOLOGY  RNA-Directed DNA
       Polymerase/METABOLISM  Spectrophotometry, Ultraviolet  Spectroscopy,
       Fourier Transform Infrared  Support, U.S. Gov't, P.H.S.  Tumor Cells,
       Cultured  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

