       Document 0463
 DOCN  M9630463
 TI    Opioid use in HIV patients with neurological changes.
 DT    9603
 AU    Paice JA; Pugliese JC; Fitzpatrick JE; Rush-Presbyterian-St. Luke's
       Medical Center, Chicago, IL, USA.
 SO    J Assoc Nurses AIDS Care. 1995 Jul-Aug;6(4):28-36. Unique Identifier :
       AIDSLINE MED/96054500
 AB    The neurological changes that are common in the HIV population may
       complicate the use of analgesics, particularly opioids. These changes,
       in combination with care providers' fear of opioids, often lead to the
       inappropriate use of antagonists, such as naloxone. Used injudiciously,
       naloxone can lead to withdrawal syndrome, return of severe pain, and
       other adverse effects. The authors describe the many disease and
       treatment-related causes for pain in patients with HIV disease, as well
       as common neurologic conditions that alter cognition and complicate the
       use of opioids. A case study is included to illustrate the dangers of
       inappropriate naloxone use.
 DE    Adult  Attitude of Health Personnel  Case Report  Female  Human  HIV
       Infections/*COMPLICATIONS  Naloxone/ADVERSE EFFECTS
       Narcotics/*THERAPEUTIC USE  Nervous System Diseases/*ETIOLOGY
       Pain/*DRUG THERAPY/ETIOLOGY  Pain Measurement  JOURNAL ARTICLE  REVIEW
       REVIEW LITERATURE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

