       Document 0454
 DOCN  M9630454
 TI    Control of drug-resistant tuberculosis.
 DT    9603
 AU    Lambregts-van Weezenbeek CS; Veen J; Royal Netherlands Tuberculosis
       Association, The Hague, The; Netherlands.
 SO    Tuber Lung Dis. 1995 Oct;76(5):455-9. Unique Identifier : AIDSLINE
       MED/96091572
 AB    Drug-resistant tuberculosis is a global problem, but the necessity and
       quality of intervention should be assessed by country since the causes
       of drug resistance, and thus the appropriate intervention strategies,
       may vary considerably between countries. An analysis of the development
       and spread of drug-resistant tuberculosis is presented and the
       respective roles of import of the disease and of HIV are discussed. A
       definition of inadequate treatment and a systematic approach to the
       quantitative and qualitative aspects of the drug resistance problem is
       proposed. The 'treatment delivery process' (TDP) is introduced as a
       diagnostic tool to analyse the causes of secondary (or acquired)
       resistance in a specific area. Intervention strategies should be based
       on the evaluation of this TDP. Intervention strategies and general
       aspects of their implementation are discussed.
 DE    Antitubercular Agents/SUPPLY & DISTRIBUTION  Delivery of Health Care
       Human  HIV Infections/COMPLICATIONS  Mutation  Mycobacterium
       tuberculosis/GENETICS  Patient Compliance  Tuberculosis/DRUG THERAPY
       Tuberculosis, Multidrug-Resistant/COMPLICATIONS/*PREVENTION &
       CONTROL/TRANSMISSION  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

