       Document 0426
 DOCN  M9630426
 TI    Levels of circulating fibronectin receptor in adult and pediatric
       patients with human immunodeficiency virus type 1 infection.
 DT    9603
 AU    Torre D; Zeroli C; Pugliese A; Giola M; Ferrario G; Bonetta G; Issi M;
       Martegani R; Speranza F; Fiori GP; Division of Infectious Diseases,
       Regional Hospital, Varese,; Italy.
 SO    Clin Diagn Lab Immunol. 1994 May;1(3):348-50. Unique Identifier :
       AIDSLINE MED/96050835
 AB    We found a significant increase in fibronectin receptor (FNR) levels in
       the sera of adult human immunodeficiency virus type 1 (HIV-1)-infected
       patients, especially in those with AIDS (1,026.9 +/- 583.9 ng/ml; P <
       0.0001). In contrast, AIDS patients with neurologic disorders and
       HIV-1-seropositive patients showed normal levels of FNR in serum. In
       addition, HIV-1-infected children showed increased levels of FNR in
       serum (824.4 +/- 333.5 ng/ml; P = 0.03). We suggest that an increase of
       FNR levels in AIDS patients is related to enhanced expression of FNR on
       HIV-1-infected cells.
 DE    Acquired Immunodeficiency Syndrome/IMMUNOLOGY  Adolescence  Adult  Child
       Child, Preschool  Female  Human  HIV Infections/*BLOOD/IMMUNOLOGY
       HIV-1/*IMMUNOLOGY  Infant  Male  Middle Age  Receptors,
       Fibronectin/*ANALYSIS/PHYSIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

