       Document 0360
 DOCN  M9630360
 TI    [Fetal cerebral accident due to massive fetomaternal hemorrhage. A case
       report]
 DT    9603
 AU    Lionnet C; Body G; Gold F; Paillet C; Vaillant MC; Alle C; Berger C;
       Centre de Diagnostic Antenatal et de Medecine Foetale, CHU; Bretonneau,
       Tours.
 SO    J Gynecol Obstet Biol Reprod (Paris). 1995;24(5):553-6. Unique
       Identifier : AIDSLINE MED/96051659
 AB    Massive fetomaternal haemorrhage (FMH) occurs in 0.12 to 0.5% of
       pregnancies. It is most often spontaneous and involves uncomplicated
       near-term pregnancies. It causes fetal anaemia, with or without fetal
       distress and hydrops fetalis. To our knowledge only one paper has
       reported a neurological complication (hemiplegia). We describe one case
       of FMH (maximal Kleihauer test = 6.5%) at 28 weeks gestation, which was
       spontaneous, reversible, associated with sinusoidal fetal heart rare
       (FHR) and hydrops fetalis; and complicated by an intraventricular
       antenatal haemorrhage at 30 weeks gestation. Echographic abnormalities
       decreased. The infant was born at 40 weeks gestation. Clinical
       examination was normal during the first week of life. At the age of 4
       1/2 months, examination showed axial hypotonia and moderated dilatation
       of intracerebral lateral ventricules without any other brain damage. At
       the age of 24 months, the child had retarded walking and hypotonia. The
       outcome was spontaneously favourable with disappearance in utero of the
       intraventricular haemorrhage (HIV), without hydrocephalia or ischaemic
       lesions. Three cases of similar FMH have been reported but none of them
       described cerebral complications. Intrauterine intravascular transfusion
       should be proposed early. No single pathophysiological mechanism of FMH
       has been universally accepted and there is no aetiological treatment.
       The risk of recurrence of FMH in later pregnancies requires careful
       follow-up.
 DE    Adult  Case Report  Cerebral Hemorrhage/*ETIOLOGY/ULTRASONOGRAPHY
       *Cerebral Ventricles  Developmental Disabilities/ETIOLOGY  English
       Abstract  Female  Fetomaternal Transfusion/*COMPLICATIONS  Follow-Up
       Studies  Hemiplegia/ETIOLOGY  Human  Infant, Newborn  Pregnancy  JOURNAL
       ARTICLE  REVIEW  REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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