       Document 0349
 DOCN  M9630349
 TI    The effect of granulocyte-macrophage colony-stimulating factor on
       myeloid cells and its clinical applications.
 DT    9603
 AU    Hill AD; Naama HA; Calvano SE; Daly JM; Department of Surgery, New York
       Hospital/Cornell University; Medical Center, New York 10021, USA.
 SO    J Leukoc Biol. 1995 Dec;58(6):634-42. Unique Identifier : AIDSLINE
       MED/96107355
 AB    Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a naturally
       occurring growth factor produced by several cell types in response to a
       variety of stimuli. GM-CSF has potent stimulatory effects on the growth
       and maturation of hematopoietic cells and has profound effects on mature
       circulating effector cells. Clinical applications of GM-CSF include
       ameliorating chemotherapy-induced neutropenia and enhancing
       hematopoietic recovery after bone marrow transplantation. This review
       evaluates the effect of GM-CSF on myeloid cells and its clinical
       applications.
 DE    Acquired Immunodeficiency Syndrome/THERAPY  Anemia, Aplastic/THERAPY
       Bone Marrow Transplantation  Granulocyte-Macrophage Colony-Stimulating
       Factor/ADVERSE EFFECTS/  *PHARMACOLOGY/THERAPEUTIC USE
       Hematopoiesis/*DRUG EFFECTS  Human  Monocytes/*DRUG EFFECTS
       Neutrophils/*DRUG EFFECTS  Signal Transduction  Support, Non-U.S. Gov't
       Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

