       Document 0305
 DOCN  M9630305
 TI    [Eosinophilic pustular folliculitis and Ofuji disease. A case report]
 DT    9603
 AU    Rotoli M; Carlesimo F; Cavalieri S; Clinica Dermatologica, Universita
       Cattolica del Sacro Cuore,; Roma.
 SO    Recenti Prog Med. 1995 Oct;86(10):386-90. Unique Identifier : AIDSLINE
       MED/96094185
 AB    We describe the case of a young man of Calabrian origin, who came to our
       observation for the appearance of erythematous pustular, intensely
       itching, lesions on the arms, trunk and, in a less extent, on the face.
       The blood count revealed a differential cell count of 16.8% eosinophils.
       Serum IgE levels were elevated (1000 IU/ml), and T cell subsets showed
       an increase in CD8+ and a decrease in CD4+ with an inversion of
       CD4+/CD8+ ratio (= 0.78). The result of the following investigations
       were either normal or negative: anti-(ds)DNA antibody, anti-nuclear
       antibody, anti-smooth muscle antibody, anti-striated muscle antibody,
       serological tests for viral, bacterial, fungal and parasitic diseases
       and cultural examination of the material from lesion. Histopathological
       examination of a biopsy specimen from the left arm showed the presence
       of abundant perivascular inflammatory infiltrate in the dermis and
       inflammatory infiltrate, with numerous eosinophils, around sebaceous
       glands. Taken together, all these data suggest the diagnosis of
       eosinophilic pustular folliculitis, a dermatosis of unknown etiology,
       with a histopathological picture identical to Ofuji's disease.
       Eosinophilic pustular folliculitis can be associated with HIV infection
       or haematological diseases (as non-Hodgkin lymphomas, myeloma, etc.); it
       was also reported in adult immunocompetent healthy individuals and in
       children. On the basis of our findings, we propose that this case should
       be classified as an idiopathic form, as we were not able to demonstrate
       any associated disease.
 DE    Adult  Anti-Inflammatory Agents, Steroidal/THERAPEUTIC USE  Case Report
       English Abstract  *Eosinophils  *Folliculitis/DRUG THERAPY/PATHOLOGY
       Follow-Up Studies  Human  Infant, Newborn  Male  Middle Age
       Prednisone/ADMINISTRATION & DOSAGE/THERAPEUTIC USE  Syndrome  Time
       Factors  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

