       Document 0259
 DOCN  M9630259
 TI    Long-term follow-up of endoscopic retrograde cholangiopancreatography
       sphincterotomy for patients with acquired immune deficiency syndrome
       papillary stenosis.
 DT    9603
 AU    Cello JP; Chan MF; Department of Medicine, University of California San
       Francisco,; USA.
 SO    Am J Med. 1995 Dec;99(6):600-3. Unique Identifier : AIDSLINE
       MED/96106294
 AB    PURPOSE: To evaluate the long-term effects on biliary-type pain and
       changes in biochemical parameters in patients with AIDS-associated
       papillary stenosis who underwent endoscopic retrograde
       cholangiopancreatography (ERCP) sphincterotomy. PATIENTS AND METHODS:
       Twenty-five consecutive patients were diagnosed by cholangiography with
       AIDS-associated papillary stenosis using standard criteria. Patients
       underwent ERCP sphincterotomy and were followed prospectively in the
       Gastrointestinal or Liver Clinics, San Francisco General Hospital, and
       by their primary physicians. Post-procedure data was prospectively
       collected by chart review or in-person or telephone interview, and
       analyzed using statistical software. RESULTS: All patients presented
       with severe right upper quadrant and/or mid-epigastric abdominal pain
       and had marked elevations of serum alkaline phosphatase. Following ERCP
       sphincterotomy, pain scores decreased significantly for at least 9
       months of follow-up. Serum alkaline phosphatase levels, however,
       remained essentially unchanged. Overall quality of life was difficult to
       assess, as patients suffered from other AIDS-associated debilitating
       diseases. CONCLUSIONS: ERCP sphincterotomy, while not without risks,
       provided significant reduction in pain in patients with AIDS-associated
       papillary stenosis.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult
       *Cholangiopancreatography, Endoscopic Retrograde  Common Bile Duct
       Diseases/ETIOLOGY/SURGERY  Constriction, Pathologic/ETIOLOGY/SURGERY
       Follow-Up Studies  Human  Male  Oddi's Sphincter/PATHOLOGY/*SURGERY
       Sphincterotomy, Endoscopic/*METHODS  CLINICAL TRIAL  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

