       Document 0234
 DOCN  M9630234
 TI    Endobronchial tuberculosis in HIV-infected patients.
 DT    9603
 AU    Calpe JL; Chiner E; Larramendi CH; Department of Respiratory Medicine,
       Villajoyosa Hospital,; Alicante, Spain.
 SO    AIDS. 1995 Oct;9(10):1159-64. Unique Identifier : AIDSLINE MED/96098132
 AB    OBJECTIVE: To evaluate the presence of endobronchial tuberculosis in
       HIV-infected patients. METHODS: Review of the clinical records of
       HIV-infected patients in whom diagnostic bronchoscopy was performed
       because of pulmonary signs or symptoms during a 3-year period. RESULTS:
       Seventy bronchoscopies were performed in 59 HIV-infected patients.
       tuberculosis was diagnosed in 25 patients, of whom six showed
       endobronchial tuberculosis. The most noteworthy radiological finding was
       mediastinal and/or hilar lymphadenopathy in five patients, occasionally
       associated with chest miliary infiltrates (in one), or a small pleural
       effusion (in two). Chest radiograph was normal in one case. The
       endoscopic findings were hyperaemia in five, caseating bronchial masses
       in four, or protrusion of extratracheal lymph nodes (broad, thickened
       carina and patchy bronchial lesions) in three out of the six patients.
       Mycobacterium tuberculosis infection was confirmed by smear and culture
       from bronchial aspirate, bronchoalveolar lavage or bronchial biopsies.
       In three cases the diagnosis was confirmed by transcarinal needle
       mediastinal puncture aspiration. Tuberculosis was the first
       opportunistic pulmonary infection in every case. The clinical course
       with standard treatment was satisfactory in all cases with no bronchial
       sequelae. CONCLUSION: Endobronchial tuberculosis may be more frequent
       than suspected in HIV-infected patients. Routine fibrobronchoscopy in
       HIV-positive patients with tuberculosis could show the true frequency of
       endobronchial tuberculosis.
 DE    Adult  Antitubercular Agents/THERAPEUTIC USE  AIDS-Related Opportunistic
       Infections/*DIAGNOSIS/DRUG THERAPY/  MICROBIOLOGY  Bronchial
       Diseases/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY  Bronchoscopy  Female
       Human  Male  Mycobacterium tuberculosis/ISOLATION & PURIF
       Tuberculosis/*DIAGNOSIS/DRUG THERAPY/MICROBIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

