       Document 0192
 DOCN  M9630192
 TI    Trends in incidence of AIDS associated with transfusion of blood and
       blood products in Europe and the United States, 1985-93.
 DT    9603
 AU    Franceschi S; Dal Maso L; La Vecchia C; Servizio di Epidemiologia,
       Centro di Riferimento Oncologico,; Aviano, Italy.
 SO    BMJ. 1995 Dec 9;311(7019):1534-6. Unique Identifier : AIDSLINE
       MED/96101226
 AB    OBJECTIVE--To quantify patterns and trends in incidence of AIDS
       associated with transfusion of blood and its products in 14 European
       countries and the United States. DESIGN--Data were derived from the
       World Health Organisation's European non-aggregate AIDS dataset and, for
       the United States, from the Centers for Disease Control AIDS public
       information dataset. Rates were standardised by using the world standard
       populations and adjusted for reporting delays in each country.
       SUBJECTS--Cases of AIDS in patients with haemophilia and recipients of
       transfusions. RESULTS--Overall, between 1985 and 1993 almost 6000 cases
       of AIDS associated with transfusions were registered in the 14 European
       countries considered and over 8000 in the United States between 1985 and
       1992. Most European countries had annual age adjusted rates lower than
       0.5 per million children aged 12 or less and between 1 and 2 per million
       adults. The United States had rates around 1 per million children and 5
       per million adults in the most recent period. For children, the highest
       rates were generally reached in 1985-7, whereas in adults the highest
       rates were in the late 1980s. France had the highest overall incidence
       of AIDS related to transfusion in Europe (3.3 per million). Romania had
       a major epidemic in children (over 30 cases per million children in
       1988-90). Incidence rates of AIDS associated with transfusion were still
       increasing in some southern European countries in the early 1990s.
       CONCLUSIONS--Apart from in France and Romania it is clear that rates of
       bloodborne AIDS in European countries are lower than those registered in
       the United States.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION
       Adolescence  Adult  Aged  Blood Component Transfusion/ADVERSE EFFECTS
       Blood Transfusion/*ADVERSE EFFECTS  Child  Child, Preschool
       Europe/EPIDEMIOLOGY  Female  Hemophilia/EPIDEMIOLOGY/THERAPY  Human
       Incidence  Infant  Infant, Newborn  Male  Middle Age  Support, Non-U.S.
       Gov't  United States/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

