       Document 0143
 DOCN  M9630143
 TI    Susceptibility of HIV to inactivation by disinfectants and ultraviolet
       light.
 DT    9603
 AU    Druce JD; Jardine D; Locarnini SA; Birch CJ; Victorian Infectious
       Diseases Reference Laboratory, Fairfield; Hospital, Fairfield,
       Australia.
 SO    J Hosp Infect. 1995 Jul;30(3):167-80. Unique Identifier : AIDSLINE
       MED/96131324
 AB    Assays were developed to assess a variety of conditions and
       presentations of infectious HIV to potential inactivating sources. A
       range of commercially available disinfectants with active constituents
       including glutaraldehyde, chlorine, phenolics, alcohol, iodine and
       quaternary ammonium compounds was tested. In addition, u.v. light was
       investigated as a potential inactivating source. All products were
       assessed against cell-free HIV in culture medium and cell-associated HIV
       suspended in medium or whole human blood. All products completely
       inactivated cell-free HIV following a 1 min exposure. However,
       cell-associated HIV was more resilient, requiring exposure of 5 min or
       more for some disinfectants. The effectiveness of the disinfectants was
       further compromised in the presence of blood.
 DE    Blood/VIROLOGY  Cell Line  Comparative Study  Culture Media
       Disinfectants/*PHARMACOLOGY  Disinfection/*METHODS  Human  HIV-1/*DRUG
       EFFECTS/RADIATION EFFECTS  Ultraviolet Rays  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

