       Document 0062
 DOCN  M9630062
 TI    [Update on microsporidiosis in humans]
 DT    9603
 AU    Atias A; Departamento de Parasitologia, Facultad de Medicina,
       Universidad; de Chile, Santiago de Chile.
 SO    Rev Med Chil. 1995 Jun;123(6):762-72. Unique Identifier : AIDSLINE
       MED/96041702
 AB    The importance of microsporidium as an opportunistic agent in
       immunocompromised and AIDS patients is reviewed. Five strains of the
       agent have been described: Encephalitozoon, Enterocytozoon, Nosema,
       Pleistophora and Septata. The clinical presentation may be as 1)
       Generalized infections with multisystemic involvement, specially of the
       central nervous system; 2) Intestinal, that is the most important and
       frequent localization in man, and that may cause death in AIDS patients;
       3) Ocular, that affects cornea, conjunctiva and may extend to paranasal
       sinuses; 4) Liver and biliary tract infection with granulomatous
       lesions, hepatic necrosis or sclerosing colangitis and 5) Muscular,
       affecting skeletal muscle. The diagnosis is difficult and is established
       finding spores in the affected tissues with light or electron
       microscopy. Lately, the diagnosis of intestinal microsporidiosis is made
       looking for faecal spores. The resistant wall of spores hampers
       treatment. However, good results are obtained with Albendazole in
       intestinal microsporidiosis.
 DE    Animal  *AIDS-Related Opportunistic Infections/DIAGNOSIS/DRUG THERAPY/
       IMMUNOLOGY  Child  Child, Preschool  English Abstract  Female  Human
       Infant  *Intestinal Diseases, Parasitic/DIAGNOSIS/DRUG
       THERAPY/IMMUNOLOGY  Male  *Microspora Infections/DIAGNOSIS/DRUG
       THERAPY/IMMUNOLOGY
       *Microsporida/CLASSIFICATION/PHYSIOLOGY/PATHOGENICITY  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

