       Document 0057
 DOCN  M9630057
 TI    [Pruritus--also a challenge in internal medicine]
 DT    9603
 AU    Brunner W; Medizinische Klinik, Kantonsspital Chur.
 SO    Schweiz Med Wochenschr. 1995 Nov 18;125(46):2244-50. Unique Identifier :
       AIDSLINE MED/96091969
 AB    Generalized or localized itch without primary skin manifestations may be
       the presenting symptom of serious internal diseases. Five characteristic
       cases of pruritus are discussed: Hodgkin's disease, primary sclerosing
       cholangitis, polycythemia vera, iron deficiency (with pica), and uremia.
       Other important causes must be considered; all forms of cholestasis,
       including primary biliary cirrhosis, drug-induced, pregnancy-related,
       and extrahepatic cholestasis; other hematologic and malignant disorders
       such as non-Hodgkin's lymphoma, leukemia, multiple myeloma, solid
       tumors, and myelodysplastic syndromes; metabolic and endocrine diseases,
       most notably diabetes mellitus, hyperthyroidism, hypothyroidism, and
       carcinoid syndrome; focal neurologic diseases such as brain tumors,
       cerebral infarctions and multiple sclerosis; adverse drug reactions
       without rash; infectious diseases, especially parasitic and HIV
       infections. A diagnostic laboratory screening for pruritus of
       undetermined origin is suggested.
 DE    Adult  Aged  Anemia, Iron-Deficiency/COMPLICATIONS  Case Report
       Cholangitis, Sclerosing/COMPLICATIONS  Diagnosis, Differential  English
       Abstract  Female  Hematologic Diseases/COMPLICATIONS  Hodgkin's
       Disease/COMPLICATIONS  Human  Liver Diseases/COMPLICATIONS  Male
       Metabolic Diseases/COMPLICATIONS  Middle Age  Pica/COMPLICATIONS
       Polycythemia Vera/COMPLICATIONS  Pruritus/CHEMICALLY
       INDUCED/DIAGNOSIS/*ETIOLOGY  Uremia/COMPLICATIONS  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

