       Document 0928
 DOCN  M9620928
 TI    Features of oral immunization.
 DT    9602
 AU    Ruedl C; Wolf H; Institute for General and Experimental Pathology,
       Medical School,; University of Innsbruck, Austria.
 SO    Int Arch Allergy Immunol. 1995 Dec;108(4):334-9. Unique Identifier :
       AIDSLINE MED/96071812
 AB    In this review, we focus on some key areas concerning the unique
       properties of the mucosal immune system. They are: (1) the fact that the
       common mucosal immune system consists of different compartments; (2) the
       advantages of oral vaccination, which can be exploited to
       antigen-specific sIgA-mediated local immune responses as well as
       systemic immunity; (3) efficacious oral immunization against respiratory
       infections; (4) oral tolerance with respect to activation of T cells
       which, after declining, can be repeatedly reinduced without changes in
       profile or magnitude, and (5) the use of transgenic plants as a new
       vaccine source for a new vaccination strategy, i.e. employing edible
       dietary vaccines.
 DE    Administration, Oral  Animal  Bacterial Infections/PREVENTION & CONTROL
       Bacterial Vaccines/*ADMINISTRATION & DOSAGE  Human  IgA,
       Secretory/IMMUNOLOGY  Immunity, Mucosal  Immunization/*METHODS  Mouth
       Mucosa/IMMUNOLOGY  Plants, Transgenic  Support, Non-U.S. Gov't  Th1
       Cells/IMMUNOLOGY  Th2 Cells/IMMUNOLOGY  Vaccination/METHODS  JOURNAL
       ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

