       Document 0575
 DOCN  M9620575
 TI    Recent advances in pediatric HIV.
 DT    9602
 AU    Menard J; Tucker NC; Darville T
 SO    J Ark Med Soc. 1995 Sep;92(4):165-8. Unique Identifier : AIDSLINE
       MED/96073484
 AB    Pediatric human immunodeficiency virus (HIV) infection is a disease of
       mother-to-infant transmission. The World Health Organization estimates
       there will be ten million HIV-infected children by the end of this
       century. It is now thought that both intrauterine and intrapartum
       transmission of HIV occurs. Infants infected in utero develop clinical
       signs and symptoms at an earlier age than those who are infected at the
       time of delivery. We describe two cases that demonstrate early-onset and
       late-onset pediatric HIV disease, respectively. Recently, it was
       determined that perinatal transmission of HIV can be significantly
       reduced by the administration of the antiretroviral drug, zidovudine
       (ZDV), to HIV-positive pregnant women and their newborns, making HIV
       screening of pregnant women more desirable than ever. A program of
       universal voluntary HIV testing for pregnant women has been successfully
       implemented at the University of Arkansas for Medical Sciences. Details
       of this program are described herein.
 DE    Case Report  Disease Transmission, Vertical  Fatal Outcome  Female
       Human  *HIV Infections/CONGENITAL/PREVENTION & CONTROL/TRANSMISSION
       Infant  Infant, Newborn  Pregnancy  *Pregnancy Complications,
       Infectious/PREVENTION & CONTROL  Zidovudine/THERAPEUTIC USE  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

