       Document 0439
 DOCN  M9620439
 TI    [Cerebral lesions in AIDS: what can be expected from scintigraphy?
       Cerebral tomographic scintigraphy using thallium-201: a contribution to
       the differential diagnosis of lymphomas and infectious lesions]
 DT    9602
 AU    Berry I; Gaillard JF; Guo Z; Cordoliani YS; Massip P; Manelfe C; Danet
       B; Service de Biophysique et Medecine Nucleaire, CHU Rangueil,;
       Toulouse.
 SO    J Neuroradiol. 1995 Sep;22(3):218-28. Unique Identifier : AIDSLINE
       MED/96043319
 AB    CT and MRI are not consistently able to differentiate central nervous
       system (CNS) lymphoma from focal cerebral infection such as
       toxoplasmosis in the human immunodeficiency virus (HIV) involvement. In
       this study thallium 201 (and/or technetium-MIBI) SPECT was performed in
       6 patients suffering from AIDS and CNS lesions. An index based on the
       ratio of thallium uptake in the lesion vs the contralateral scalp was
       calculated. In 4 out of 5 patients with lymphoma (3 confirmed by biopsy,
       2 highly suspected on CT and resistance to antitoxoplasmosis treatment)
       focal lesions showed high uptake of thallium. On the other hand one
       markedly necrotic lymphoma and all infectious lesions did not take up
       thallium. This suggests a role for thallium 201 brain SPECT in the
       workup of focal CNS lesions in AIDS.
 DE    Adult  AIDS-Related Opportunistic Infections/*RADIONUCLIDE IMAGING
       Brain Neoplasms/*RADIONUCLIDE IMAGING  Case Report  Diagnosis,
       Differential  English Abstract  Female  Human  Lymphoma,
       AIDS-Related/*RADIONUCLIDE IMAGING  Magnetic Resonance Imaging  Male
       Middle Age  Technetium Tc 99m Sestamibi/DIAGNOSTIC USE  Thallium
       Radioisotopes/*DIAGNOSTIC USE  *Tomography, Emission-Computed,
       Single-Photon  Tomography, X-Ray Computed  Toxoplasmosis,
       Cerebral/*RADIONUCLIDE IMAGING  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

