       Document 0432
 DOCN  M9620432
 TI    The changing spectrum of pulmonary infections due to nontuberculous
       mycobacteria.
 DT    9602
 AU    Boggs DS; University of Oklahoma Health Sciences Center, Division of;
       Pulmonary and Critical Care Medicine, Oklahoma City, USA.
 SO    J Okla State Med Assoc. 1995 Sep;88(9):373-82. Unique Identifier :
       AIDSLINE MED/96033393
 AB    Although nontuberculous mycobacteria (NTM) infections are not common,
       there is evidence that they are becoming increasingly recognized and in
       some parts of the country occur more frequently than M. tuberculosis.
       The classic description of NTM pulmonary infection is that of a male
       patient with cavitary infiltrates and predisposing lung disease. With an
       increase in the number of reported cases of infection, there have been
       other syndromes described, particularly in elderly female patients
       without any predisposing conditions, those with asymptomatic pulmonary
       nodules, esophageal disease causing recurrent aspiration pneumonitis,
       and disseminated infection in AIDS. Therapy of M. avium complex (MAC)
       disease is far from definitive whereas infections due to M. kansasii can
       be effectively treated even in the presence of profound
       immunosuppression. Recognition of these infections and their recent
       change in epidemiology hopefully will encourage practitioners to enroll
       their patients into clinical protocols that will help to establish the
       optimal regimen(s).
 DE    Causality  Esophageal Diseases/MICROBIOLOGY  Female  Human  Incidence
       Lung Diseases/COMPLICATIONS/DIAGNOSIS/DRUG THERAPY/EPIDEMIOLOGY/
       *MICROBIOLOGY  Male  Mycobacterium avium Complex  *Mycobacterium
       Infections, Atypical/COMPLICATIONS/DIAGNOSIS/DRUG  THERAPY/EPIDEMIOLOGY
       Mycobacterium, Atypical/ISOLATION & PURIF  JOURNAL ARTICLE  REVIEW
       REVIEW LITERATURE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

