       Document 0349
 DOCN  M9620349
 TI    [Type 2 human immunodeficiency virus infection (HIV-2) in Spain:
       analysis of the first 50 cases. Spanish Group for the Study of HIV-2]
 DT    9602
 AU    Soriano V; Gutierrez M; Caballero E; Aguilera A; Cilla G; Lopez I;
       Instituto de Salud Carlos III, Madrid.
 SO    Med Clin (Barc). 1995 Sep 9;105(7):241-5. Unique Identifier : AIDSLINE
       MED/96059191
 AB    BACKGROUND: Infection by the human immunodeficiency virus type 2 (HIV-2)
       is endemic in West Africa where it is responsible for many AIDS cases.
       HIV-2 has been described in subjects in other countries, mainly in
       African immigrants, although it may also be found in natives. The first
       cases of HIV-2 infection were identified in Spain in 1988. METHODS: The
       clinical, epidemiologic and virologic characteristics of the subjects
       with HIV-2 infection identified in Spain up to November 1994 are
       described. RESULTS: Fifty people have been diagnosed with HIV-2
       infection, being found mainly around the large urban centers (20 cases
       in Madrid and 16 in Barcelona). All the cases were African immigrants
       except for 10 Spaniards (20%), 6 of whom had acquired the infection in
       endemic areas while the other 4 (one prostitute from Barcelona and 3
       bisexual males from Guipuzcoa) had acquired the infection in Spain.
       Heterosexual transmission was implicated in all the cases except in 6
       subjects (4 bisexual males, one case of probable intravenous
       transmission and one vertically infected child). Eight (all Spanish)
       patients have developed AIDS and 5 have died to date. At least 10 other
       subjects have a CD4+ lymphocyte count lower than 0.2 x 10(9)/l, one
       being the only pediatric patient (6-year-old male). CONCLUSIONS: HIV-2
       infection is present in Spain, although there is no evidence for a rapid
       dissemination of the virus outside the collective of African immigrants.
       The Spaniards with HIV-2 infection represent 20% of the cases having
       contracted the virus through sexual relations with natives from endemic
       areas.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY  Adult  Aged  English
       Abstract  Female  Human  HIV Seropositivity/*EPIDEMIOLOGY  *HIV-2
       Infant  Male  Middle Age  Spain/EPIDEMIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

