       Document 0331
 DOCN  M9620331
 TI    Detection of diverse HIV-1 genetic subtypes in the USA.
 DT    9602
 AU    Brodine SK; Mascola JR; Weiss PJ; Ito SI; Porter KR; Artenstein AW;
       Garland FC; McCutchan FE; Burke DS; Health Sciences and Epidemiology
       Department, Naval Health; Research Center, San Diego, CA 92186, USA.
 SO    Lancet. 1995 Nov 4;346(8984):1198-9. Unique Identifier : AIDSLINE
       MED/96054841
 AB    Of the nine genetic subtypes of HIV-1 that exist world wide, subtype B
       predominates in North America and Europe. Thus, most knowledge about
       HIV-1 and most vaccine development efforts are based on subtype B
       viruses. We document here the detection of HIV-1 subtypes A, D, and E in
       five US servicemen who acquired these non-subtype-B infections during
       overseas deployments. The dispersal of diverse HIV-1 subtypes into
       regions of the world with previously restricted genetic diversity may
       have important implications for the epidemiology of the epidemic and for
       the design and implementation of vaccine trials.
 DE    Acquired Immunodeficiency Syndrome/*TRANSMISSION/VIROLOGY  Adult  Female
       Human  HIV-1/CLASSIFICATION/*GENETICS  Male  *Military Personnel
       Support, U.S. Gov't, Non-P.H.S.  Travel  United States  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

