       Document 0287
 DOCN  M9620287
 TI    Cryptococcosis in a cat seropositive for feline immunodeficiency virus.
 DT    9602
 AU    Cabanes FJ; Abarca ML; Bonavia R; Bragulat MR; Castella G; Ferrer L;
       Faculty of Veterinary Medicine, Autonomous University of; Barcelona,
       Spain.
 SO    Mycoses. 1995 Mar-Apr;38(3-4):131-3. Unique Identifier : AIDSLINE
       MED/96046117
 AB    A 5-year-old female Siamese cat was presented to the veterinary teaching
       hospital with a history of bronchopneumonia for 20 days. The cat had not
       responded to antibacterial chemotherapy and had developed a pronounced
       submandibular lymphadenopathy. Characteristically encapsulated yeast
       cells with narrow-necked buds were clearly seen in a fine-needle
       aspirate of the lymph node with an India ink preparation. Cryptococcus
       neoformans var. neoformans was identified. Susceptibility tests on the
       isolated strain were performed using antifungal tablets. The strain was
       sensitive to amphotericin B, fluconazole, itraconazole and ketoconazole
       and was resistant to 5-fluorocytosine. The cat was positive for feline
       immunodeficiency virus. Nevertheless, the cat was treated with
       ketoconazole for 3 months and apparently recovered. Three months later
       the animal was presented in a precomatose state. The owners refused to
       treat the animal and the cat was destroyed.
 DE    Animal  Antifungal Agents/PHARMACOLOGY  Case Report  Cats
       Cryptococcosis/*COMPLICATIONS/DIAGNOSIS  Cryptococcus neoformans/DRUG
       EFFECTS/GROWTH & DEVELOPMENT/  *ISOLATION & PURIF  Feline Acquired
       Immunodeficiency Syndrome/*COMPLICATIONS  Female  *Immunodeficiency
       Virus, Feline  Microbial Sensitivity Tests  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

