       Document 0180
 DOCN  M9620180
 TI    Analysis of antral biopsy specimens for evidence of acquired
       mucosa-associated lymphoid tissue in HIV1-seropositive and HIV1-negative
       patients.
 DT    9602
 AU    Eidt S; Schrappe M; Fischer R; Institute of Pathology, University of
       Cologne, Germany.
 SO    Scand J Gastroenterol. 1995 Jul;30(7):635-9. Unique Identifier :
       AIDSLINE MED/96063241
 AB    BACKGROUND: There is conflicting evidence concerning the prevalence of
       Helicobacter pylori gastritis in HIV1-infected patients. Furthermore, a
       possible influence of immunodeficiency on the acquisition of
       mucosa-associated lymphoid tissue (MALT) in the antral mucosa remains to
       be elucidated. METHODS: Seventy-seven consecutive HIV1-infected patients
       (mean age, 40.2 years) were compared in a prospective study with 77
       HIV1-negative age-matched patients, using immunohistochemical stainings.
       RESULTS: In HIV1-infected patients the prevalence of H. pylori gastritis
       was lower and the inflammatory reaction less pronounced than in
       controls. Lymphoid follicles and intraepithelial B cells were
       significantly more often detected in HIV1-negative patients.
       CONCLUSIONS: Evidence of acquired MALT is only rarely found in
       HIV1-infected patients. These findings might contribute to the
       explanation of why low-grade gastric MALT lymphomas have not been
       reported in HIV1-infected patients so far.
 DE    Adult  Biopsy  Female  Gastric Mucosa/IMMUNOLOGY/MICROBIOLOGY/PATHOLOGY
       Gastritis/IMMUNOLOGY/MICROBIOLOGY/*PATHOLOGY  Helicobacter
       pylori/*ISOLATION & PURIF  Helicobacter Infections/IMMUNOLOGY/*PATHOLOGY
       Human  HIV Infections/IMMUNOLOGY/MICROBIOLOGY/PATHOLOGY  HIV
       Seronegativity/IMMUNOLOGY  HIV
       Seropositivity/IMMUNOLOGY/MICROBIOLOGY/*PATHOLOGY  HIV-1  Lymphoma,
       Mucosa-Associated Lymphoid Tissue/IMMUNOLOGY/  MICROBIOLOGY/*PATHOLOGY
       Male  Middle Age  Prospective Studies  Pyloric
       Antrum/MICROBIOLOGY/*PATHOLOGY  Serodiagnosis  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

