       Document 0151
 DOCN  M9620151
 TI    [Blood donors seropositive for type 1 human immunodeficiency virus
       (HIV-1). Epidemiologic characteristics and clinical course]
 DT    9602
 AU    Altes A; Muniz-Diaz E; Madoz P; Verger G; Martino R; Puig L; Servicio de
       Hemoterapia, Hospital de la Santa Creu i Sant Pau de; Barcelona.
 SO    Sangre (Barc). 1995 Aug;40(4):269-74. Unique Identifier : AIDSLINE
       MED/96063457
 AB    PURPOSES: To evaluate retrospectively the epidemiologic profile and
       clinical course of the HIV-positive voluntary blood donors in the Sant
       Pau's Hospital Blood Bank (Barcelona-Spain) between 1986 and 1993.
       PATIENTS AND METHODS: A total of 119,345 blood donors were studied, and
       fifty seven such cases were identified. Risk behavior, causes of failure
       of the pre-donation procedures and clinical stage were analyzed. A
       follow-up of their infection was performed by the Infectious Disease
       Unit. RESULTS: The mean age of 57 seropositive donors was 31 +/- 8
       years. Prevalence of HIV-1 infection among donors was 0.48 per 1000.
       Forty four (77%) were male and 13 (23%) female. Forty three (75%) were
       first time donors while 14 (25%) were repeat donors. The causes for the
       failure of the self-deferral questionnaire were: 42 subjects did not
       consider that they had engaged in risk behavior, seven donors lied in
       order to know if they were HIV carriers and two cases were driven to
       donate due to social or family pressure. The distribution of these
       donors according to risk behaviour was: 30 (53%) heterosexual, 11 (20%)
       homosexual, 11 (20%) intravenous drug users and five (7%) with no
       identified risk. It was noted that HIV infection progressed more rapidly
       to AIDS in HIV - positive homosexual donors than in heterosexual
       subjects (p < 0.05). CONCLUSIONS: Heterosexual donors who maintain
       sexual contacts with different partners without prophylactic measures
       for HIV infection currently represent the highest risk group for
       transfusion-related HIV infection. Clinical evolution of HIV infection
       was faster and more devastating in the homosexual group than in the
       heterosexual group.
 DE    Adult  *Blood Donors  English Abstract  Female  Follow-Up Studies  Human
       HIV Seropositivity/*EPIDEMIOLOGY  *HIV-1  Male  Prevalence
       Retrospective Studies  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

