       Document 0113
 DOCN  M9620113
 TI    Performance evaluation of a particle agglutination test for antibody to
       human immunodeficiency virus 1: comparison with enzyme immunoassay.
 DT    9602
 AU    Elavia AJ; Thomas A; Nandi J; Coyaji GD; Bhavalkar-Potdar V; Department
       of Blood Bank, Jehangir Hospital and Medical Centre,; Pune, India.
 SO    Vox Sang. 1995;69(1):23-6. Unique Identifier : AIDSLINE MED/96078297
 AB    A performance evaluation of a particle agglutination test (PAT),
       manufactured by Fujirebio Inc., Japan (Serodia-HIV), for antibody to
       human immunodeficiency virus type-1 (anti-HIV-1) was carried out and
       compared with a currently available enzyme immunoassay (EIA),
       manufactured by Genetic Systems Corp., USA, (HIV-1/HIV-2 EIA). Testing
       2,878 Indian donor and patient samples, both tests showed 100%
       sensitivity and comparable specificity (PAT: 99.8%; EIA: 99.7% among
       donor samples). We conclude that PAT is a specific and sensitive test
       for anti-HIV-1; it is simple to perform and does not require
       sophisticated equipment. Hence it is suitable for mass screening of
       blood donors in a developing country like India, especially in rural
       areas where presently no HIV-testing facilities are available.
 DE    *Agglutination Tests  Comparative Study  Evaluation Studies  Human  HIV
       Antibodies/*BLOOD  HIV-1/*ISOLATION & PURIF  *Immunoenzyme Techniques
       India  Mass Screening/METHODS  Predictive Value of Tests  Retrospective
       Studies  Sensitivity and Specificity  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

