       Document 0688
 DOCN  M9620688
 TI    Acute lung disease in the immunocompromised host. Diagnostic accuracy of
       the chest radiograph.
 DT    9602
 AU    Logan PM; Primack SL; Staples C; Miller RR; Muller NL; Department of
       Radiology, University of British Columbia,; Vancouver, Canada.
 SO    Chest. 1995 Nov;108(5):1283-7. Unique Identifier : AIDSLINE MED/96064611
 AB    PURPOSE: To assess the diagnostic accuracy of the chest radiograph in
       the evaluation of acute pulmonary complications in immunocompromised
       patients. METHODS: The study included the chest radiographs in 149
       consecutive acute pulmonary complications seen in immunocompromised
       patients in whom a definitive diagnosis was made. Twenty-four
       complications were in patients with AIDS and 125 were in non-AIDS
       patients. The radiographs were separately reviewed in random order by
       two independent observers. The observers assessed pattern and
       distribution of radiographic findings and recorded their first-choice
       diagnosis. RESULTS: The most common complication in patients with AIDS
       was Pneumocystis carinii pneumonia (n = 21). In the non-AIDS patients,
       the most common complications included invasive aspergillosis (n = 25),
       drug reaction (n = 21), and Pneumocystis pneumonia (n = 20). A correct
       first-choice diagnosis was made in 90% of patients with AIDS and 34% of
       non-AIDS patients. IN AIDS patients with Pneumocystis pneumonia, the
       correct first-choice diagnosis was made in 41 of 42 (98%) readings by
       the two observers. In non-AIDS patients with invasive pulmonary
       aspergillosis, drug reaction, and Pneumocystis pneumonia, the correct
       first-choice diagnosis was made in 38%, 26%, and 43% of readings,
       respectively. CONCLUSION: The chest radiograph is helpful in the
       differential diagnosis of acute lung disease in the immunocompromised
       host, particularly in patients with AIDS.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS  Acute Disease
       Adolescence  Adult  Aged  Aged, 80 and over  Female  Human
       *Immunocompromised Host  Lung
       Diseases/COMPLICATIONS/IMMUNOLOGY/*RADIOGRAPHY  Male  Middle Age
       Pneumonia, Pneumocystis carinii/COMPLICATIONS/RADIOGRAPHY  Predictive
       Value of Tests  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

