       Document 0963
 DOCN  M9620963
 TI    Sinonasal non-Hodgkin's lymphoma in patients infected with human
       immunodeficiency virus: report of three cases and review.
 DT    9602
 AU    Pomilla PV; Morris AB; Jaworek A; Department of Medicine, Baystate
       Medical Center, Springfield,; Massachusetts 01199, USA.
 SO    Clin Infect Dis. 1995 Jul;21(1):137-49. Unique Identifier : AIDSLINE
       MED/96065627
 AB    Non-Hodgkin's lymphoma (NHL) is a frequent complication of human
       immunodeficiency virus (HIV) infection, but involvement of the sinonasal
       region has only rarely been reported. We report three cases of
       AIDS-associated sinonasal NHL that occurred at our institution and
       review eight cases that were reported in the literature. The
       epidemiological and clinicopathologic features of these cases are
       described and compared with those of three other groups of patients:
       non-HIV-infected patients with sinonasal NHL, HIV-infected patients with
       NHL of any anatomic site, and HIV-infected patients with infectious
       sinusitis. Patients with AIDS-associated sinonasal NHL more frequently
       developed bony erosion and presented with signs and symptoms referable
       to adjacent structures, such as the orbit, than did HIV-infected
       patients with sinusitis, and patients with AIDS and NHL less frequently
       had typical sinus symptoms and diffuse sinus involvement than did
       patients with sinusitis. However, the clinical manifestations of these
       conditions overlap; thus a high index of suspicion for NHL is imperative
       for prompt diagnosis. These lymphomas typically are high-grade and
       disseminate early, and the prognosis is generally poor.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/IMMUNOLOGY  Adult  Case
       Report  Comparative Study  CD4 Lymphocyte Count  Female  Human  HIV
       Infections/*COMPLICATIONS/IMMUNOLOGY  Lymphoma,
       Non-Hodgkin's/*ETIOLOGY/PATHOLOGY/RADIOTHERAPY  Male  Paranasal Sinus
       Neoplasms/*ETIOLOGY/PATHOLOGY/RADIOTHERAPY  Paranasal
       Sinuses/PATHOLOGY/RADIOGRAPHY  Tomography, X-Ray Computed  JOURNAL
       ARTICLE  REVIEW  REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

