       Document 0913
 DOCN  M9620913
 TI    Pending problem of silent human immunodeficiency virus infection.
 DT    9602
 AU    Bentwich Z; Bar-Yehuda S; Nagai K; Wainberg MA; Kalinkovich A;
       Jehuda-Cohen T; Ruth Ben Ari Institute of Clinical Immunology, Kaplan
       Hospital,; Hebrew University Medical School, Rehovot, Israel.
 SO    Cell Mol Biol (Noisy-le-grand). 1995 May;41(3):345-50. Unique Identifier
       : AIDSLINE MED/96059392
 AB    The problem of silent HIV infection is reviewed. Overall, the number of
       proven silent infection in several at-risk populations, including HIV
       exposed health-care workers, homosexuals, IV drug addicts and children
       born to HIV-infected mothers, has been very low. Contrary to these
       observations, we describe a very high prevalence of HIV specific
       immunity and positive HIV specific PCR signals in an Ethiopian immigrant
       population recently arrived in Israel. The interpretation of these
       findings is not entirely clear but we suggest that host immunity and
       probably different handling of the infection may account for the longer
       persistence of viral components in the body. Further studies are
       required to determine the amount and nature of these viral elements and,
       most importantly, whether they are still infectious.
 DE    Acquired Immunodeficiency Syndrome/DIAGNOSIS/*EPIDEMIOLOGY/
       IMMUNOLOGY/TRANSMISSION  B-Lymphocytes/IMMUNOLOGY  Carrier State
       Emigration and Immigration  Ethiopia/ETHNOLOGY  Female  Human  HIV
       Antigens/IMMUNOLOGY  *HIV Seronegativity  HIV-1/GENETICS/*IMMUNOLOGY
       Israel/EPIDEMIOLOGY  Male  Risk Factors  T-Lymphocytes/IMMUNOLOGY
       JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

