       Document 0482
 DOCN  M9620482
 TI    [Studies on maternal transmission of HIV-1]
 DT    9602
 AU    Tabei Y; Sadamasu K; Mori K; Monma K; Sekine H; Kudoh Y; Miyazawa Y;
       Okada K; Department of Microbiology, Tokyo Metropolitan Research;
       Laboratory of Public Health.
 SO    Kansenshogaku Zasshi. 1995 Aug;69(8):858-63. Unique Identifier :
       AIDSLINE MED/96083296
 AB    To investigate HIV-1 transmission from mother to child, samples taken
       from 3 HIV-1 sero-positive pregnant mothers, 3 children born by
       caesareans from their mothers and therapeutic abortion from 2 HIV-1
       sero-positive mothers were tested for HIV-1 antibody by westernblot, p24
       antigen by antigen captured ELISA, proviral DNA by Nested-PCR and
       isolation of HIV-1 virus from peripheral blood, cord blood, amniotic
       fluid and placenta. HIV-1 proviral DNA was detected in the peripheral
       blood of all mothers, but p24 antigen and virus isolation were not
       detected. None of the HIV-1 markers, except for antibody, was detected
       in the samples from their children and placenta. These facts strongly
       suggest that there was no HIV-1 transmission from mother to child.
 DE    AIDS Serodiagnosis  Base Sequence  *Disease Transmission, Vertical  DNA,
       Viral/ANALYSIS  English Abstract  Female  Human  HIV
       Seropositivity/DIAGNOSIS/*TRANSMISSION  HIV-1/GENETICS/ISOLATION & PURIF
       Infant  Infant, Newborn  Molecular Sequence Data  Polymerase Chain
       Reaction  Pregnancy  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

