       Document 0128
 DOCN  M9620128
 TI    [Kaposi sarcoma. An epidemiological perspective]
 DT    9602
 AU    Lecker S; Melbye M; Center for epidemiologisk grundforskning, Statens
       Seruminstitut,; Kobenhavn.
 SO    Ugeskr Laeger. 1995 Sep 18;157(38):5232-6. Unique Identifier : AIDSLINE
       MED/96075142
 AB    Prior to the 1980s, Kaposi's sarcoma was a rare tumour diagnosed three
       to four times more frequently among men than women. It was primarily
       seen among elderly men of Mediterranean or Jewish descent, in
       well-defined areas of Central Africa, or more scattered as individual
       cases with underlying immunosuppression. Geographical restrictions and
       suggested associations with certain HLA-types gave rise to early
       speculations of a genetic component involved in its etiology. With the
       AIDS epidemic, the epidemiology of Kaposi's sarcoma changed drastically.
       Although diagnosed among AIDS patients that are transfusion recipients,
       intravenous drug users and haemophiliacs, Kaposi's sarcoma is primarily
       found in homosexual men with AIDS among whom the risk has increased to
       100,000 compared to the general population. Specific behaviours linked
       to homosexual men have been sought to explain this relationship, but
       accumulating evidence favours the involvement of an infectious agent in
       the etiology of Kaposi's sarcoma. The most promising candidate today is
       a possible new herpesvirus, similar to but distinct from Herpes-virus
       saimiri and Epstein-Barr virus.
 DE    Africa/EPIDEMIOLOGY  AIDS-Related Opportunistic Infections  Bisexuality
       English Abstract  Europe/EPIDEMIOLOGY  Female  Homosexuality, Male
       Human  Immunocompromised Host  Male  Sarcoma,
       Kaposi's/*EPIDEMIOLOGY/ETIOLOGY/VIROLOGY  *World Health  JOURNAL ARTICLE
       REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

