       Document 0428
 DOCN  M9620428
 TI    [Spinal cord toxoplasmosis and AIDS]
 DT    9602
 AU    Carteret M; Petit E; Granat O; Marichez M; Gilquin J; Service de
       Radiologie, Hopital Saint-Joseph, Paris.
 SO    J Radiol. 1995 Jul;76(7):453-5. Unique Identifier : AIDSLINE
       MED/96011912
 AB    Toxoplasmosis is the most common brain parasitic infection in acquired
       immunodeficiency syndrome (AIDS). Spinal cord localisations are still
       rare (2 cases with cerebral involvement, 2 cases without). A case of
       both spinal cord and cerebral involvement is reported. MR imaging was
       performed because of sensory level (L1). A focal conus medullaris
       enlargement was seen, iso intense on T1 weighted images. This lesion was
       hyperintense on T2 weighted sequence, and was homogeneously enhanced
       after Gadolinium on T1 weighted images. A medullary oedema was noted. A
       toxoplasmosis treatment was initiated, without corticotherapy. MR
       imaging performed one month later (D30), while important clinical
       improvements were seen, pointed out normal thickness of conus
       medullaris, without enhancement after Gadolinium. Disease lesions in
       AIDS with focal spinal cord processes are reviewed, and diagnostic
       work-up is discussed. Spinal cord single lesion, associated or not with
       brain involvements should be treated as a toxoplasmic infection, with MR
       imaging follow up. This work up should avoid medullary biopsy, still
       required in case of treatment failure. Cerebral involvements, with
       multiples lesions, can mask medullary localisation.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  Adult  AIDS-Related
       Opportunistic Infections/DIAGNOSIS  Case Report  English Abstract  Human
       Magnetic Resonance Imaging  Male  Spinal Cord
       Diseases/DIAGNOSIS/*ETIOLOGY/PARASITOLOGY
       Toxoplasmosis/DIAGNOSIS/*ETIOLOGY  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

