       Document 1000
 DOCN  M9621000
 TI    Inducible nitric oxide synthase in the central nervous system.
 DT    9602
 AU    Sparrow JR; Department of Ophthalmology, Cornell University Medical
       College,; New York, NY 10021, USA.
 SO    J Mol Neurosci. 1994-95;5(4):219-29. Unique Identifier : AIDSLINE
       MED/96101969
 AB    There is an accumulation of evidence indicating that induction of the
       calcium-independent isoform of nitric oxide synthase (iNOS) in glial
       cells can contribute to nitric oxide-mediated neural-cell damage.
       Elucidation of iNOS inducing signals and mechanisms regulating its
       augmentation and suppression may have implications for our understanding
       of basic processes underlying some forms of central nervous system
       disease.
 DE    Animal  Astrocytes/ENZYMOLOGY  AIDS Dementia
       Complex/ENZYMOLOGY/PATHOLOGY  Brain Diseases/ENZYMOLOGY/PATHOLOGY  Cell
       Death  Central Nervous System/*ENZYMOLOGY
       Encephalitis/ENZYMOLOGY/PATHOLOGY  Enzyme Induction  Human
       Isoenzymes/BIOSYNTHESIS/PHYSIOLOGY  Mice  Nerve Tissue
       Proteins/BIOSYNTHESIS/*PHYSIOLOGY  Neuroglia/ENZYMOLOGY
       Neurons/PATHOLOGY  Nitric Oxide/METABOLISM  Nitric-Oxide
       Synthase/BIOSYNTHESIS/*PHYSIOLOGY  Rats  JOURNAL ARTICLE  REVIEW
       REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

