       Document 0414
 DOCN  M9620414
 TI    Acupuncture for the treatment of cocaine addiction. Investigation of a
       needle puncture control.
 DT    9602
 AU    Avants SK; Margolin A; Chang P; Kosten TR; Birch S; Yale University
       School of Medicine, CMHC/Substance Abuse Center,; New Haven, CT 06519,
       USA.
 SO    J Subst Abuse Treat. 1995 May-Jun;12(3):195-205. Unique Identifier :
       AIDSLINE MED/96030114
 AB    We conducted a 6-week, single-blind study of acupuncture for cocaine
       dependence in methadone-maintained patients (N = 40) for the purpose of
       identifying an appropriate needle puncture control for use in future
       large-scale clinical trials. Patients were randomly assigned to receive
       daily acupuncture in three auricular sites plus one body site (LI-4), or
       in control sites within 2-3 mm of the four active sites. Overall, there
       was a positive response to treatment on a variety of drug-related and
       psychosocial measures. Cocaine use decreased significantly for patients
       in both needle puncture groups. The only statistically significant
       difference between the two types of needle puncture was on ratings of
       craving. Subjects rated each type of needle puncture as equally credible
       and perceived no significant differences on the acute effects of the two
       types of needle insertions. Power calculations based on these findings
       suggest that very large sample sizes would be required to detect
       treatment differences between this control condition and active
       acupuncture. Alternative controls are suggested, and the challenges
       inherent in implementing controlled clinical trials of acupuncture are
       discussed.
 DE    Acupuncture Points  *Acupuncture Therapy  Adult  *Cocaine  Combined
       Modality Therapy  Comorbidity  Comparative Study  Ear, External  Female
       Human  HIV Seropositivity/TRANSMISSION  Male  Methadone/THERAPEUTIC USE
       Middle Age  Narcotic Dependence/REHABILITATION  Single-Blind Method
       Substance Abuse, Intravenous/REHABILITATION  Substance
       Dependence/*REHABILITATION  Substance Withdrawal Syndrome/PREVENTION &
       CONTROL  Support, U.S. Gov't, P.H.S.  Treatment Outcome  CLINICAL TRIAL
       JOURNAL ARTICLE  RANDOMIZED CONTROLLED TRIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

