       Document 0867
 DOCN  M9620867
 TI    Clinical and chest radiographic features of tuberculosis associated with
       human immunodeficiency virus in Zimbabwe.
 DT    9602
 AU    Pozniak AL; MacLeod GA; Ndlovu D; Ross E; Mahari M; Weinberg J;
       Department of Medicine, University of Zimbabwe, Harare, Zimbabwe.
 SO    Am J Respir Crit Care Med. 1995 Nov;152(5 Pt 1):1558-61. Unique
       Identifier : AIDSLINE MED/96048814
 AB    In the developing world, the diagnosis of tuberculosis is dependent on
       clinical and radiologic features as culture facilities are not readily
       available. It has been reported that tuberculosis in HIV-positive
       persons can present with atypical clinical and radiographic features.
       The object of this study was to examine how often atypical features
       occur in HIV-positive compared with HIV-negative persons and how these
       findings correspond to sputum-smear findings. Detailed demographic,
       clinical, and chest radiographic features of tuberculosis were assessed
       in 202 HIV-positive adults and 220 HIV-negative patients admitted
       consecutively. Using univariate analysis, several of these features were
       found to be significantly associated with being HIV-positive, but after
       multiple regression analysis only, age group (15 to 42 yr), a negative
       tuberculin response, intrathoracic lymphadenopathy, and lack of
       cavitation but not sputum-smear status remained significant.
 DE    Adolescence  Adult  Aged  AIDS-Related Opportunistic
       Infections/*DIAGNOSIS  Child  Child, Preschool  Comparative Study
       Female  Human  HIV Seronegativity  HIV Seropositivity/DIAGNOSIS
       *HIV-1/IMMUNOLOGY  Infant  Logistic Models  Lung/*RADIOGRAPHY  Male
       Middle Age  Sputum/MICROBIOLOGY  Tuberculin Test/STATISTICS & NUMER DATA
       Tuberculosis, Pulmonary/*DIAGNOSIS  Zimbabwe  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

