       Document 0549
 DOCN  M9620549
 TI    Unusual clinical manifestation of a disfiguring necrobiotic
       granulomatous disease.
 DT    9602
 AU    Willemsen M; De Coninck A; Goossens A; DeCree J; Roseeuw D; Department
       of Dermatology, Free University of Brussels, Belgium.
 SO    J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):887-90. Unique Identifier :
       AIDSLINE MED/96055069
 AB    A 39-year-old woman had a disfiguring granulomatous disease of 36 years'
       duration. Nodules appeared on her lower extremities and later extended
       to her face; this led to ulceration and destruction of the nasal
       cartilage. This disease of unknown origin does not conform to any
       previously described entity. Some patients with a similar case
       presentation have been observed in France.
 DE    Adult  Biopsy  Case Report  CD4-CD8 Ratio  Female  Granulomatous
       Disease, Chronic/*DIAGNOSIS/DRUG THERAPY/IMMUNOLOGY  Human  Leg  Nasal
       Septum  Necrobiotic Disorders/*DIAGNOSIS/DRUG THERAPY/IMMUNOLOGY  Nose
       Skin/MICROBIOLOGY/PATHOLOGY  JOURNAL ARTICLE  REVIEW  REVIEW OF REPORTED
       CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

