       Document 0931
 DOCN  M9620931
 TI    Abnormalities of visual spatial attention in HIV infection and the
       HIV-associated dementia complex.
 DT    9602
 AU    Maruff P; Malone V; McArthur-Jackson C; Mulhall B; Benson E; Currie J;
       Neurophysiology and Neurovisual Research Unit, Mental Health; Research
       Institute of Victoria, Parkville, Australia.
 SO    J Neuropsychiatry Clin Neurosci. 1995 Summer;7(3):325-33. Unique
       Identifier : AIDSLINE MED/96076004
 AB    Covert orienting of visuospatial attention (COVAT) was examined in 88
       homosexual or bisexual men: 12 with mild HIV-associated dementia complex
       (ADC), 30 neurologically intact with AIDS (NI-AIDS), 23 asymptomatic
       HIV+ (HIV+ASX), and 23 HIV-negative control subjects. In mild ADC, COVAT
       was normal for spatial but impaired for nonspatial cues; 17% of NI-AIDS
       and HIV+ASX subjects had similar COVAT impairment patterns and also
       showed cognitive deficits. HIV+ subjects with normal COVAT showed normal
       cognitive performance. Impairment of nonspatial attentional processing
       in the ADC subjects and subgroups of the neurologically intact HIV+
       subjects may reflect early subcortical dysfunction caused by HIV
       infection. COVAT assessment may be sensitive for detection of early
       subclinical neurological impairment in HIV infection.
 DE    Adult  Affect  Age Factors  Attention/*PHYSIOLOGY  AIDS Dementia
       Complex/*PSYCHOLOGY  Human  HIV Infections/*PSYCHOLOGY  Male
       Neuropsychological Tests  Orientation/PHYSIOLOGY  Psychometrics
       Reaction Time/PHYSIOLOGY  Space Perception/*PHYSIOLOGY  Visual
       Perception/*PHYSIOLOGY  CLINICAL TRIAL  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

