       Document 0933
 DOCN  M9620933
 TI    [A study on effect of qingwen granule in regulating immunological
       function in infantile respiratory viral infection]
 DT    9602
 AU    Zhang GC; Li ZH; Shen Q; Dept. of Pediatrics, Xijing Hospital, Fouth
       Military Medical; University, Xi'an.
 SO    Chung Kuo Chung Hsi I Chieh Ho Tsa Chih. 1995 Jul;15(7):408-10. Unique
       Identifier : AIDSLINE MED/96041555
 AB    To evaluate the effect of Qing-wen Granule (QWG) on immunological
       function, T lymphocyte subsets and interferon gamma(INF-gamma)
       expression cells in peripheral blood mononuclear cells, lymphocyte
       transformation rate and the level of salivary secretory IgA (sIgA) were
       determined by alkaline phosphatase antialkaline phosphatase (APAAP)
       technique or 3H-TdR incorporation with lymphocyte stimulation index(SI)
       or agar single immunodiffusion in infantile respiratory viral infection.
       The results showed that the percentage of CD3, CD4, and CD4/CD8 ratio of
       patients treated with QWG for 3 days were not significantly different in
       comparing with the control group untreated with QWG (P > 0.05), but the
       values of IFN-gamma expression cell, SI and the level of sIgA were more
       markedly increased than that of control (P < 0.05). It suggested that
       the QWG could improve and regulate immune function in infantile
       respiratory viral infection.
 DE    Adjuvants, Immunologic/PHARMACOLOGY  Child, Preschool  CD4-CD8 Ratio
       Drugs, Chinese Herbal/*PHARMACOLOGY/THERAPEUTIC USE  English Abstract
       Female  Human  IgA, Secretory/BLOOD  Infant  Interferon Type II/BLOOD
       Lymphocyte Transformation/DRUG EFFECTS  Male  Pneumonia, Viral/DRUG
       THERAPY/IMMUNOLOGY  Respiratory Tract Infections/DRUG
       THERAPY/*IMMUNOLOGY/VIROLOGY  T-Lymphocyte Subsets/*IMMUNOLOGY  Virus
       Diseases/DRUG THERAPY/*IMMUNOLOGY  CLINICAL TRIAL  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

