       Document 0621
 DOCN  M9610621
 TI    HIV incidence among New Haven needle exchange participants: updated
       estimates from syringe tracking and testing data.
 DT    9601
 AU    Kaplan EH; Heimer R; Yale School of Management, Yale University, New
       Haven,; Connecticut, USA.
 SO    J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):175-6.
       Unique Identifier : AIDSLINE MED/96007280
 AB    This article provides updated estimates of the rate of new HIV
       infections among participants in New Haven's legal needle exchange
       program from syringe tracking and testing data. We previously reported
       that based on data collected from November 1990 through May 1992, the
       maximum likelihood incidence rate was zero with a 95% confidence
       interval of 0-10.2 new infections per 100 drug injectors per year.
       Expanding this data set through August 1993, the same statistical
       methods yield a maximum likelihood estimate of 1.63 new infections per
       100 drug injectors per year with a 95% confidence interval of 0-7.2.
       Given these data, the null hypothesis of no new infections cannot be
       rejected, providing further support for the efficacy of New Haven's
       needle exchange program.
 DE    Confidence Intervals  Connecticut/EPIDEMIOLOGY  DNA, Viral/ANALYSIS
       Human  HIV Infections/*EPIDEMIOLOGY  HIV-1/*GENETICS  Incidence
       Likelihood Functions  *Needle-Exchange Programs  Needles  Patient
       Participation  Polymerase Chain Reaction  Proviruses/*GENETICS
       Substance Abuse, Intravenous/COMPLICATIONS  Support, Non-U.S. Gov't
       Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

