       Document 0620
 DOCN  M9610620
 TI    Human immunodeficiency virus type-1 seroconversion trends among young
       adults serving in the United States Army, 1985-1993. United States
       Military Medical Consortium for Applied Retroviral Research.
 DT    9601
 AU    Renzullo PO; McNeil JG; Wann ZF; Burke DS; Brundage JF; Division of
       Preventive Medicine, Walter Reed Army Institute of; Research,
       Washington, DC, USA.
 SO    J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Oct 1;10(2):177-85.
       Unique Identifier : AIDSLINE MED/96007281
 AB    The direct measurement of the incidence of new infections with the human
       immunodeficiency virus type 1 (HIV-1) can be made among soldiers because
       of the routine and periodic nature of HIV-1 testing in the United States
       Army. Between November 1985 and October 1993, 978 HIV-1 seroconversions
       were seen among 1,061,768 soldiers, contributing over 3.6 million
       person-years of follow-up [seroconversion rate (95% confidence interval)
       = 0.27/1,000 person-years (0.25-0.29)]. A significant decreasing trend
       in HIV-1 seroconversion rates was seen over the analysis period. The
       rate of new infections declined significantly from the first interval,
       1985-1987, (0.43/1,000 person-years) to the second interval, 1987-1988,
       (0.28/1,000 person-years), but stabilized at approximately 0.22/1,000
       person-years after 1988, representing new infections in approximately
       100-150 soldiers annually. The risk of seroconversion among active duty
       soldiers was significantly associated with racial/ethnic group, age,
       gender, and marital status. Surveillance of HIV-1 seroconversion rates
       in the U.S. Army continues to offer a unique opportunity to assess
       temporal trends in the evolving HIV-1 infection epidemic. Monitoring the
       rate of new HIV-1 infections allows for identification of subgroups in
       need of intervention, refocusing of intervention strategies, and
       evaluation of their effectiveness.
 DE    Adult  Age Distribution  Cohort Studies  Ethnic Groups  Female  Human
       HIV Infections/*EPIDEMIOLOGY  HIV Seropositivity/*EPIDEMIOLOGY  *HIV-1
       Incidence  Male  Marital Status  *Military Personnel  Multivariate
       Analysis  Sex Distribution  Time Factors  United States/EPIDEMIOLOGY
       JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

