       Document 0605
 DOCN  M9610605
 TI    The epidemic of HIV/AIDS in Abidjan, Cote d'Ivoire: a review of data
       collected by Projet RETRO-CI from 1987 to 1993.
 DT    9601
 AU    Djomand G; Greenberg AE; Sassan-Morokro M; Tossou O; Diallo MO; Ekpini
       E; Ghys P; Soro B; Brattegaard K; Yapi A; et al; Projet RETRO-CI,
       Abidjan, Cote d'Ivoire.
 SO    J Acquir Immune Defic Syndr Hum Retrovirol. 1995 Nov 1;10(3):358-65.
       Unique Identifier : AIDSLINE MED/96027804
 AB    We present a review of epidemiologic data collected by Projet RETRO-CI
       between 1987 and 1993 on trends in human immunodeficiency virus type 1
       (HIV-1) and HIV-2 infections and on cases of AIDS in Abidjan, Cote
       d'Ivoire. Overall rates of HIV infection in pregnant women had already
       reached 10% in 1987, and have increased only modestly since then. In
       contrast, in 1992-1993, rates in men with sexually transmitted diseases
       and in female commercial sex workers reached 27 and 86%, respectively.
       The increases in infection rates have been largely due to transmission
       of HIV-1, whereas rates of HIV-2 have remained stable or have declined.
       Among persons with tuberculosis and hospitalized patients, rates of
       46-71% have been reached, increases in recent years again being largely
       attributable to HIV-1. Among the 15,245 AIDS cases reported by Projet
       RETRO-CI, a steady decline in the male:female sex ratio has occurred
       over time, from 4.8:1 in 1988 to 1.9:1 in 1993. It is likely that AIDS
       cases were initially concentrated among a core group of female
       commercial sex workers and their male clients. A substantial proportion
       of sex workers and their clients originate from neighboring countries,
       and migration is likely to have contributed to the spread of HIV
       infection in West Africa. Including HIV-associated pulmonary
       tuberculosis as an AIDS-defining illness increased AIDS cases reported
       by Projet RETRO-CI by 13% in 1993. Despite a need for interventional
       research, careful description of the evolution of HIV/AIDS in this
       region remains essential.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION
       Adolescence  Adult  Age Distribution  Child  Child, Preschool  Cote
       d'Ivoire/EPIDEMIOLOGY  *Disease Outbreaks  Disease Transmission,
       Horizontal  Disease Transmission, Vertical  Female  Human  HIV
       Antibodies/ANALYSIS  HIV Infections/*EPIDEMIOLOGY/TRANSMISSION  HIV
       Seroprevalence  *HIV-1/IMMUNOLOGY  *HIV-2/IMMUNOLOGY  Infant  Infant,
       Newborn  Male  Middle Age  Population Surveillance  Pregnancy  Pregnancy
       Complications, Infectious/EPIDEMIOLOGY  Prostitution  Retrospective
       Studies  Seroepidemiologic Methods  Sexually Transmitted
       Diseases/EPIDEMIOLOGY  Tuberculosis, Pulmonary/TRANSMISSION  JOURNAL
       ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

