       Document 0570
 DOCN  M9610570
 TI    Correlative morphologic and functional imaging for diagnosis, staging
       and follow up in AIDS: an overview.
 DT    9601
 AU    Brunetti A; Soricelli A; Rotondo A; Alfano B; Raman R; Celentano L; Di
       Chiro G; Salvatore M; Centro CNR per la Medicina Nucleare, Fondazione
       Pascale, Naples,; Italy.
 SO    Q J Nucl Med. 1995 Sep;39(3):201-11. Unique Identifier : AIDSLINE
       MED/96033589
 AB    The immunocompromised patient can be affected by different opportunistic
       infections and tumors, that can involve all organ systems, and
       particularly, the central nervous system, the respiratory system, the
       gastrointestinal tract. The extreme variability of AIDS presentations
       requires a specific preparation and cooperation between the different
       diagnostic imaging specialists and a close collaboration with the
       clinicians. With AIDS, different morphologic and functional imaging
       techniques can be used for detection of disease sites, assessment of the
       extent of the disease and monitoring of disease changes over time and
       response to treatment. The complexity of AIDS presentations is such that
       full integration of the complementary information obtained with
       different techniques could be most useful. Image registration
       (coregistration, fusion) indicates approaches where precise spatial
       cross-references are obtained, in order to combine the information
       acquired with different imaging modalities, in particular by blending
       morphologic CT/MRI data with functional SPET/PET data. In this paper, an
       overview of the developments in the field of image fusion follows some
       comments on the results of morphologic and functional assessment of
       brain, chest and abdominal diseases in the course of AIDS, as
       illustrative examples of the potential benefits of multimodality image
       correlation.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/*DIAGNOSIS
       AIDS-Related Opportunistic Infections/DIAGNOSIS  Diagnostic Imaging
       Human  JOURNAL ARTICLE  REVIEW  REVIEW, TUTORIAL

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

