       Document 0514
 DOCN  M9610514
 TI    [Pseudomesotheliomatous carcinoma in HIV infection]
 DT    9601
 AU    Brunner-La Rocca HP; Schlossberg D; Vogt P; Medizinische Klinik,
       Kantonsspital Baden.
 SO    Dtsch Med Wochenschr. 1995 Sep 29;120(39):1312-7. Unique Identifier :
       AIDSLINE MED/96013582
 AB    HISTORY AND FINDINGS: A 32-year-old man, known to have been HIV-positive
       for 6 years, was admitted to hospital because of dyspnoea and dry cough.
       For 8 months he had an HIV illness in stage C3 (Center for Disease
       Control and Prevention, Atlanta) with fever, weight loss and obviously
       reduced general and nutritional state. There was almost total
       auscultatory dullness over the right hemithorax and the chest radiogram
       showed massive right pleural effusion, as well as broad pleural deposits
       which were suspicious of tumours. The first pleural aspiration recovered
       1000 ml exudate. An infectious cause could not be identified. As the
       effusion was refractory to treatment (301 of effusion were drained over
       several days), thoracoscopy was performed despite the patient's poor
       general condition. It revealed extensive tumour masses over the right
       pleura. COURSE: After the endoscopy the patient's condition deteriorated
       rapidly and he died 3 weeks after admission, only 1 1/2 months after
       onset of the first symptoms. Histological examination of the
       endoscopically obtained biopsy revealed large-cell carcinoma. The form
       of growth indicated that it was a pseudomesotheliomatous carcinoma.
       CONCLUSION: No previous case of this type of tumour in an HIV-positive
       patient has been reported. This patient's course was less favourable
       than is expected in those without HIV infection.
 DE    Adult  Case Report  Chronic Disease  English Abstract  Fatal Outcome
       Human  HIV Infections/*DIAGNOSIS/PATHOLOGY  *HIV-1  Lung/PATHOLOGY  Lung
       Neoplasms/*DIAGNOSIS/PATHOLOGY  Male  Mesothelioma/*DIAGNOSIS/PATHOLOGY
       Pleural Effusion, Malignant/DIAGNOSIS/PATHOLOGY  JOURNAL ARTICLE  REVIEW
       REVIEW OF REPORTED CASES

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

