       Document 0503
 DOCN  M9610503
 TI    Retinal detachment in AIDS-related cytomegalovirus retinitis.
 DT    9601
 AU    Sandy CJ; Bloom PA; Graham EM; Ferris JD; Shah SM; Schulenburg WE;
       Migdal CS; Western Eye Hospital, London, UK.
 SO    Eye. 1995;9 ( Pt 3):277-81. Unique Identifier : AIDSLINE MED/96014799
 AB    Patients with acquired immune deficiency syndrome (AIDS) and
       cytomegalovirus retinitis (CMVR) are surviving longer due to the use of
       virostatic medicines and improved treatment of opportunistic infections.
       As a result, retinal detachment is likely to become an increasingly
       common cause of visual morbidity in these patients. The incidence and
       outcome of retinal detachment complicating CMVR was studied at two
       London AIDS centres. Patients with CMVR were identified prospectively
       and underwent standard treatment. Retinal detachments were diagnosed
       during regular follow-up. If retinal reattachment surgery was performed,
       a standard procedure of vitrectomy and silicone oil internal tamponade
       was employed. Of 147 patients with CMVR, 41 (28%) developed retinal
       detachments (47 eyes). Forty-three detachments were rhegmatogenous and 4
       were exudative. Fifteen eyes of 9 patients with rhegmatogenous
       detachments underwent retinal reattachment surgery. Of these, visual
       acuity remained stable or improved in 12 eyes (80%) in the immediate
       post-operative period. At the last clinic visit, 8 eyes (53%) maintained
       a visual acuity of 6/60 or better. The visual results of surgery are
       good in selected patients, bearing in mind the progressive nature of the
       underlying disease and poor life expectancy.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS  AIDS-Related
       Opportunistic Infections/*COMPLICATIONS  Cytomegalovirus
       Retinitis/*COMPLICATIONS  Human  Prospective Studies  Retinal
       Detachment/*ETIOLOGY/SURGERY  Silicone Oils/ADMINISTRATION & DOSAGE
       Treatment Outcome  Visual Acuity  Vitrectomy  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

