       Document 0436
 DOCN  M9610436
 TI    Comparison of periodontal disease in HIV seropositive subjects and
       controls (I). Clinical features.
 DT    9601
 AU    Smith GL; Cross DL; Wray D; Department of Oral Medicine and Oral
       Pathology, University of; Edinburgh, Scotland, UK.
 SO    J Clin Periodontol. 1995 Jul;22(7):558-68. Unique Identifier : AIDSLINE
       MED/96045108
 AB    The aims of this study were to investigate the prevalence and severity
       of periodontal diseases in HIV seropositive and assumed HIV seronegative
       individuals in the Edinburgh area. 29 HIV seropositive subjects were
       examined at baseline and at 3-monthly intervals. Attachment loss and
       dichotomous indicators of periodontal disease were recorded. 27 control
       subjects were seen at baseline only. Although there was no significant
       difference between the 2 groups in terms of mean attachment loss at
       baseline, HIV seropositive subjects had experienced more severe
       attachment loss localised to the lower incisor region. HIV seropositive
       subjects had a significantly higher mean % of sites exhibiting
       suppuration and redness. A distinct subgroup of 9 HIV seropositive
       subjects with widespread attachment loss was detected, which included
       those subjects with severely affected lower incisors. Site-specific
       attachment loss of > or = 3 mm was observed in only 20 sites out of 2814
       sites in HIV+subjects observed longitudinally. The incidence of
       aggressive periodontal disease in this study was lower than anticipated,
       despite the inclusion of patients with advanced HIV infection or AIDS.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS/PATHOLOGY  Adult
       Case-Control Studies  Comparative Study  Cross-Sectional Studies
       Disease Progression  Female  Follow-Up Studies  Forecasting  Human  HIV
       Infections/COMPLICATIONS/PATHOLOGY  HIV Seronegativity  HIV
       Seropositivity/*COMPLICATIONS/PATHOLOGY  Incidence  Incisor
       Longitudinal Studies  Male  Periodontal Attachment
       Loss/COMPLICATIONS/PATHOLOGY  Periodontal
       Diseases/*COMPLICATIONS/PATHOLOGY  Periodontal
       Pocket/COMPLICATIONS/PATHOLOGY  Prevalence  Scotland  Support, Non-U.S.
       Gov't  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

