       Document 0434
 DOCN  M9610434
 TI    CT features of pulmonary nocardiosis.
 DT    9601
 AU    Buckley JA; Padhani AR; Kuhlman JE; Russell H. Morgan Department of
       Radiology and Radiological; Sciences, Johns Hopkins Medical
       Institutions, Baltimore, MD, USA.
 SO    J Comput Assist Tomogr. 1995 Sep-Oct;19(5):726-32. Unique Identifier :
       AIDSLINE MED/96024780
 AB    OBJECTIVE: Our goal was to identify the CT features of pulmonary
       nocardiosis, specifically in AIDS patients versus other
       immunocompromised hosts. MATERIALS AND METHODS: Twenty-four patients
       with pulmonary nocardiosis were identified; medical records, CT scans,
       and chest radiographs were reviewed. Five patients had HIV disease, 17
       had other causes of immunosuppression, and 2 had normal immunity.
       RESULTS: CT features of pulmonary nocardiosis included one or more
       nodules/masses (20/24 cases, 83%), cavitation (8, 33%),
       consolidation/infiltrates (8, 33%), and pleural thickening (7, 29%). All
       AIDS patients with nocardiosis had multiple (four or more) nodules
       detected on CT and 80% (4/5) had cavitation compared with 21% each of
       non-AIDS patients (p < 0.01 for multiple nodules, p < 0.045 for
       cavitation). CONCLUSION: CT features of pulmonary nocardiosis are
       varied, and AIDS patients are more likely to display cavitation and
       multiple nodules. Although not widely recognized, Nocardia infection
       should be included in the differential diagnosis of an unexplained
       nodule or progressive cavitary process in HIV-positive patients.
 DE    Adult  Aged  AIDS-Related Opportunistic Infections/RADIOGRAPHY  Chronic
       Disease  Coin Lesion, Pulmonary/MICROBIOLOGY/RADIOGRAPHY  Diagnosis,
       Differential  Female  Follow-Up Studies  Human  HIV Seropositivity
       Immunocompromised Host  Immunosuppression  Lung
       Diseases/*MICROBIOLOGY/*RADIOGRAPHY  Male  Middle Age  Nocardia
       Infections/*RADIOGRAPHY  Pleural Diseases/MICROBIOLOGY/RADIOGRAPHY
       Pleural Effusion/MICROBIOLOGY/RADIOGRAPHY  Retrospective Studies
       Thoracic Radiography  *Tomography, X-Ray Computed  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

