       Document 0396
 DOCN  M9610396
 TI    Risk factors for postcoital bleeding among women with or at risk for
       infection with human immunodeficiency virus.
 DT    9601
 AU    Padian NS; Abrams J; Skurnick JH; Van Devanter NL; O'Brien TR;
       Department of Obstetrics, Gynecology, and Reproductive Sciences,;
       University of California, San Francisco 94110, USA.
 SO    J Infect Dis. 1995 Oct;172(4):1084-7. Unique Identifier : AIDSLINE
       MED/96029379
 AB    Risk factors for postcoital bleeding were examined in 475 women who were
       enrolled in a study of heterosexual transmission of human
       immunodeficiency virus (HIV). In bivariate analyses, history of sexually
       transmitted diseases (STDs; P = .03), HIV infection (P = .008), and
       dyspareunia or pain during intercourse (P = .0001) were significant risk
       factors. In multivariate analysis, the two latter factors remained
       significant (for HIV, odds ratio [OR] = 2.1, P = .02, 95% confidence
       interval [CI] = 1.1-4.0; for dyspareunia, OR = 3.5, P < .001, 95% CI =
       1.8-6.6), as did the interaction term of STD history and heavy smoking
       (OR = 2.4, P = .02, 95% CI = 1.2-5.0). Pain during intercourse was the
       strongest predictor of postcoital bleeding but may be part of the same
       phenomenon. Similarly, because this study relied on cross-sectional
       data, the direction of the causal pathway linking HIV to postcoital
       bleeding cannot be established. However, these data suggest that
       smoking, a modifiable risk factor, may increase risk of postcoital
       bleeding and contribute to susceptibility for HIV and other STDs.
 DE    Adult  Analysis of Variance  *Coitus  Female  *Hemorrhage  Human  HIV
       Infections/*TRANSMISSION  Risk Factors  Support, U.S. Gov't, P.H.S.
       Vagina/*PATHOLOGY  JOURNAL ARTICLE  MULTICENTER STUDY

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).

